Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

Kazuma Yoshizumi; Kaeko Murota; Shiro Watanabe; Hironori Tomi; Tomoko Tsuji; Junji Terao

doi:10.1271/bbb.70761

Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

Kazuma Yoshizumi, Kaeko Murota, Shiro Watanabe, Hironori Tomi, Tomoko Tsuji, Junji Terao^*

^*Corresponding author for this work

Section of Host Defences, Division of Bioscience, Institute of Natural Medicine

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

Original language	English
Pages (from-to)	1126-1129
Number of pages	4
Journal	Bioscience, biotechnology, and biochemistry
Volume	72
Issue number	4
DOIs	https://doi.org/10.1271/bbb.70761
State	Published - 2008

Keywords

3, 4-seco-lupane triterpenoid saponin
Acanthopanax sessiliflorus
Chiisanoside
Intestinal absorption
Lipase inhibitor

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1271/bbb.70761

Cite this

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title = "Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents",

abstract = "Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.",

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author = "Kazuma Yoshizumi and Kaeko Murota and Shiro Watanabe and Hironori Tomi and Tomoko Tsuji and Junji Terao",

year = "2008",

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language = "英語",

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T1 - Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

AU - Yoshizumi, Kazuma

AU - Murota, Kaeko

AU - Watanabe, Shiro

AU - Tomi, Hironori

AU - Tsuji, Tomoko

AU - Terao, Junji

PY - 2008

Y1 - 2008

N2 - Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

AB - Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

KW - 3, 4-seco-lupane triterpenoid saponin

KW - Acanthopanax sessiliflorus

KW - Chiisanoside

KW - Intestinal absorption

KW - Lipase inhibitor

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U2 - 10.1271/bbb.70761

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SN - 0916-8451

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JO - Bioscience, biotechnology, and biochemistry

JF - Bioscience, biotechnology, and biochemistry

IS - 4

ER -

Chiisanoside is not absorbed but inhibits oil absorption in the small intestine of rodents

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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