@inproceedings{3ee1dcb713be4071a2890eb2d867c17a,
title = "Characterization of cancer metastasis in model mice by multiphoton microscopy and Raman spectroscopy",
abstract = "Raman spectroscopy provides a wealth of diagnostic information to the surgeon with in situ cancer detection and labelfree histopathology in clinical practice. However, to identify cancer diagnostic biomarkers in vivo is still challenging, because malignancy can be characterized not only by the cancer cells but also by the environmental factors. Here we investigate molecular dynamics in both cancer cells and their environment in xenograft models and spontaneous metastasis models using Raman spectroscopy and nonlinear optical imaging. We are constructing a custom-designed Raman spectral imaging system to reveal the metastasis process and to evaluate therapeutics toward the clinical application of the technique.",
keywords = "Cancer metastasis, Raman spectroscopy, SHG imaging, cancer diagnosis, multiphoton microscopy",
author = "Yusuke Oshima and Shigehiro Koga and Hiromi Yamamoto and Yuji Watanabe",
note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; Biomedical Imaging and Sensing Conference 2018 ; Conference date: 25-04-2018 Through 27-04-2018",
year = "2018",
doi = "10.1117/12.2317041",
language = "英語",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Toyohiko Yatagai and Yoshihisa Aizu and Osamu Matoba and Yasuhiro Awatsuji and Yuan Luo",
booktitle = "Biomedical Imaging and Sensing Conference",
}
