C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study

Keyphrases

• 3D-QSAR Model 16%
• Aldehydes 16%
• Amyloglucosidase 100%
• Antidiabetic Drugs 16%
• Casuarine 100%
• CoMFA Model 16%
• CoMSIA Model 16%
• Electrostatic Field 16%
• Fluorinated 100%
• Fluorine Atom 33%
• Fluoro 16%
• Glycosidase 33%
• Hydrogen Bonds (H-bonds) 16%
• Hydroxyl 16%
• Iminosugars 33%
• Immunomodulatory 16%
• Inhibitor Structure 100%
• Inhibitor Synthesis 100%
• Inhibitory Activity 16%
• Ion-ion Interaction 16%
• Maltase 16%
• Molecular Docking Calculations 33%
• Newly Established 16%
• Nucleophilic Fluorination 16%
• Organocatalytic 16%
• Parent Compounds 16%
• Polyhydroxylated 16%
• Potent Inhibitor 16%
• Pyrrolizidine 16%
• Specific Inhibitor 16%
• Stereoselective Fluorination 16%
• Structure-activity Relationship Studies 100%
• Systematic Structure 16%
• Trehalase 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Alpha Glucosidase 16%
• Antidiabetic Agent 16%
• Glucan 1,4 Alpha Glucosidase 100%
• Glycosidase 16%
• Iminosugar 33%
• Pyrrolizidine 16%
• Quantitative Structure-Activity Relationship 16%
• Structure Activity Relationship 100%
• Trehalase 33%