Burst-wave-aided contrast-enhanced active Doppler ultrasonography can visualize the viscosity of a Newtonian fluid in a channel

Kenji Yoshida*, Masaaki Omura, Shinnosuke Hirata, Tadashi Yamaguchi

*この論文の責任著者

研究成果: ジャーナルへの寄稿学術論文査読

抄録

This study investigates the dependence of the translational velocity of lipid-coated microbubbles in an ultrasound field on the viscosity of the surrounding Newtonian fluid. Plane burst waves with a center frequency of 7.34 MHz were used to uniformly drive microbubbles with a radius of 1.4 ± 0.3 μm (mean ± standard deviation) in a flow channel. Bubbles were detected using the Doppler method using pulse waves with a center frequency of 5.2 MHz, and the velocities of individual bubbles were analyzed by tracking them in consecutive images. Examinations were conducted at various viscosities from 1 to 3 mPa∙s. The experimentally determined velocity-viscosity relationship qualitatively agreed with numerical simulations. This was written as a power-law dependence and used as a calibration curve to evaluate the local viscosity coefficient for the trajectories of individual bubbles. We succeeded in demonstrating viscosity imaging by multiplying the obtained viscosity coefficient with the bubble trajectories, convoluted with the point spread function of ultrasound imaging.

本文言語英語
論文番号03SP73
ジャーナルJapanese Journal of Applied Physics
64
3
DOI
出版ステータス出版済み - 2025/03/01

ASJC Scopus 主題領域

  • 工学一般
  • 物理学および天文学一般

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