抄録
This study investigates the dependence of the translational velocity of lipid-coated microbubbles in an ultrasound field on the viscosity of the surrounding Newtonian fluid. Plane burst waves with a center frequency of 7.34 MHz were used to uniformly drive microbubbles with a radius of 1.4 ± 0.3 μm (mean ± standard deviation) in a flow channel. Bubbles were detected using the Doppler method using pulse waves with a center frequency of 5.2 MHz, and the velocities of individual bubbles were analyzed by tracking them in consecutive images. Examinations were conducted at various viscosities from 1 to 3 mPa∙s. The experimentally determined velocity-viscosity relationship qualitatively agreed with numerical simulations. This was written as a power-law dependence and used as a calibration curve to evaluate the local viscosity coefficient for the trajectories of individual bubbles. We succeeded in demonstrating viscosity imaging by multiplying the obtained viscosity coefficient with the bubble trajectories, convoluted with the point spread function of ultrasound imaging.
本文言語 | 英語 |
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論文番号 | 03SP73 |
ジャーナル | Japanese Journal of Applied Physics |
巻 | 64 |
号 | 3 |
DOI | |
出版ステータス | 出版済み - 2025/03/01 |
ASJC Scopus 主題領域
- 工学一般
- 物理学および天文学一般