ASymmetric Synthesis Of 2-Propylisofagomine Using Allylic Hydroxy Group Accelerated Ring-Closing Enyne Metathesis

Tatsuya Taguchi; Tatsushi Imahori; Yuichi Yoshimura; Atsushi Kato; Isao Adachi; Masatoshi Kawahata; Kentaro Yamaguchi; Hiroki Takahata

doi:10.3987/COM-11-S(P)74

ASymmetric Synthesis Of 2-Propylisofagomine Using Allylic Hydroxy Group Accelerated Ring-Closing Enyne Metathesis

Tatsuya Taguchi^*, Tatsushi Imahori, Yuichi Yoshimura, Atsushi Kato, Isao Adachi, Masatoshi Kawahata, Kentaro Yamaguchi, Hiroki Takahata

^*この論文の責任著者

薬剤部

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

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An asymmetric synthesis of 2-propylisofagomine 5 using allylic hydroxy group accelerated ring-closing enyne metathesis (AHA-RCEM) was conducted with high diastereoselectivity in 13% overall yield starting from the commercially available (E)-hex-2-ol.

本文言語	英語
ページ（範囲）	929-944
ページ数	16
ジャーナル	Heterocycles
巻	84
号	2
DOI	https://doi.org/10.3987/COM-11-S(P)74
出版ステータス	出版済み - 2012

ASJC Scopus 主題領域

分析化学
薬理学
有機化学

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10.3987/COM-11-S(P)74

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title = "ASymmetric Synthesis Of 2-Propylisofagomine Using Allylic Hydroxy Group Accelerated Ring-Closing Enyne Metathesis",

abstract = "An asymmetric synthesis of 2-propylisofagomine 5 using allylic hydroxy group accelerated ring-closing enyne metathesis (AHA-RCEM) was conducted with high diastereoselectivity in 13% overall yield starting from the commercially available (E)-hex-2-ol.",

author = "Tatsuya Taguchi and Tatsushi Imahori and Yuichi Yoshimura and Atsushi Kato and Isao Adachi and Masatoshi Kawahata and Kentaro Yamaguchi and Hiroki Takahata",

year = "2012",

doi = "10.3987/COM-11-S(P)74",

language = "英語",

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AU - Taguchi, Tatsuya

AU - Imahori, Tatsushi

AU - Yoshimura, Yuichi

AU - Kato, Atsushi

AU - Adachi, Isao

AU - Kawahata, Masatoshi

AU - Yamaguchi, Kentaro

AU - Takahata, Hiroki

PY - 2012

Y1 - 2012

N2 - An asymmetric synthesis of 2-propylisofagomine 5 using allylic hydroxy group accelerated ring-closing enyne metathesis (AHA-RCEM) was conducted with high diastereoselectivity in 13% overall yield starting from the commercially available (E)-hex-2-ol.

AB - An asymmetric synthesis of 2-propylisofagomine 5 using allylic hydroxy group accelerated ring-closing enyne metathesis (AHA-RCEM) was conducted with high diastereoselectivity in 13% overall yield starting from the commercially available (E)-hex-2-ol.

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U2 - 10.3987/COM-11-S(P)74

DO - 10.3987/COM-11-S(P)74

M3 - 学術論文

AN - SCOPUS:84856555743

SN - 0385-5414

VL - 84

SP - 929

EP - 944

JO - Heterocycles

JF - Heterocycles

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ASymmetric Synthesis Of 2-Propylisofagomine Using Allylic Hydroxy Group Accelerated Ring-Closing Enyne Metathesis

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