抄録
This paper describes a convenient synthetic procedure for nucleoside mimics, 1-6, in which the 3′,5′-hydroxy groups of natural 2′-deoxythymidine or 2′-deoxyadenosine are replaced by thiol, amine, or alkylthiol groups. Such nucleosides would be built up into a single DNA strand with cooperative participation of metal coordination, where internucleoside linkages are replaced by metal complexation motifs. The X-ray crystal structure and complexation behaviors of 3′,5′-dithiothymidine, 1, with AuI are also reported.
本文言語 | 英語 |
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ページ(範囲) | 331-338 |
ページ数 | 8 |
ジャーナル | Journal of Organic Chemistry |
巻 | 68 |
号 | 2 |
DOI | |
出版ステータス | 出版済み - 2003/01/24 |
ASJC Scopus 主題領域
- 有機化学