@article{320e7a589791444b97955ebda76edacd,
title = "Alternative formation of red-shifted channelrhodopsins: Noncovalent incorporation with retinal-based enamine-type schiff bases and mutated channelopsin",
abstract = "Red-shifted channelrhodopsins (ChRs) are attractive for optogenetic tools. We developed a new type of red-shifted ChRs that utilized noncovalent incorporation of retinal and 3,4-dehydroretinal-based enamine-type Schiff bases and mutated channelopsin, C1C2-K296G. These ChRs exhibited absorption maxima that were shifted 10-30 nm toward longer wavelengths than that of C1C2-ChR regenerated with alltrans- retinal.",
keywords = "Channelrhodopsin, Chromophore, Neuroscience, Optogenetics, Red-shift",
author = "Takashi Okitsu and Take Matsuyama and Takahiro Yamashit and Toru Ishizuk and Hiromu Yawo and Yasushi Imamoto and Yoshinori Shichid and Akimori Wada",
note = "Publisher Copyright: {\textcopyright} 2017 The Pharmaceutical Society of Japan.",
year = "2017",
doi = "10.1248/cpb.c17-00054",
language = "英語",
volume = "65",
pages = "356--358",
journal = "Chemical and Pharmaceutical Bulletin",
issn = "0009-2363",
publisher = "Pharmaceutical Society of Japan",
number = "4",
}