@article{b3ee6e7453e94881bb6c879778e038f9,
title = "Absolute configuration of pterocidin, a potent inhibitor of tumor cell invasion from a marine-derived Streptomyces",
abstract = "During the course of screening natural products for the inhibitors of tumor cell invasion, pterocidin, a linear polyketide with a δ-lactone terminus, was rediscovered from a Streptomyces strain of a marine sediment-origin. A series of J-based configuration analyses and NOESY analysis, coupled with chemical derivatization and chiral anisotropy analysis, established the absolute stereochemistry of five asymmetric centers in this compound.",
keywords = "Absolute configuration, Invasion inhibitor, Pterocidin, Streptomyces",
author = "Yasuhiro Igarashi and Daisuke Asano and Kazuo Furihata and Naoya Oku and Satoshi Miyanaga and Hiroaki Sakurai and Ikuo Saiki",
note = "Funding Information: We acknowledge the Atmosphere and Ocean Research Institute, the University of Tokyo and Dr. C. Imada at Tokyo University of Marine Science and Technology for assistance to sediment sampling. This research was supported in part by a research Grant from the Atmosphere and Ocean Research Institute, University of Tokyo to Y.I. ",
year = "2012",
month = feb,
day = "8",
doi = "10.1016/j.tetlet.2011.11.115",
language = "英語",
volume = "53",
pages = "654--656",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd.",
number = "6",
}
