抄録
A housekeeping basolateral Cl- channel in rabbit gastric parietal cells (0.3-0.4 pS) is closed by an intracellular application of GTP gamma S. Here, we found a novel GTP gamma S-dependent regulatory mechanism, in which GTP gamma S stimulates intracellular superoxide (O2-) production and the O2- acts as a messenger in the closure of the Cl- channel. Other oxygen species such as .OH and H2O2 were not involved in the closing mechanism.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | S301-302 |
| ジャーナル | Japanese Journal of Physiology |
| 巻 | 44 Suppl 2 |
| 出版ステータス | 出版済み - 1994 |
ASJC Scopus 主題領域
- 生理学