A new ionone derivative from the leaves of Picrasma quassioides

Chang Liu; Rong Rong Cheng; Zhu zhen Han; Ying bo Yang; Yue Zhou; Li Yang; Zheng Tao Wang

doi:10.1080/10286020.2018.1464561

A new ionone derivative from the leaves of Picrasma quassioides

Chang Liu, Rong Rong Cheng, Zhu zhen Han, Ying bo Yang, Yue Zhou, Li Yang, Zheng Tao Wang^*

^*この論文の責任著者

がん細胞生物学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

抄録

Nigakialcohol A (1), as unusual cyclization ionone derivative, together with eight known ones (2–9), were isolated from the leaves of Picrasma quassioides (D. Don) Benn (Simaroubaceae). Their structures were elucidated by extensive spectroscopic analyses and comparison with literature data. Compound 2 showed a weak inhibitory effect on NO production at non-cytotoxic concentration (100 μM) with inhibitory rate of 59%, and thus it should be regarded as potential anti-inflammatory agents.

本文言語	英語
ページ（範囲）	652-658
ページ数	7
ジャーナル	Journal of Asian Natural Products Research
巻	21
号	7
DOI	https://doi.org/10.1080/10286020.2018.1464561
出版ステータス	出版済み - 2019/07/03

ASJC Scopus 主題領域

分析化学
分子医療
薬理学
薬科学
創薬
補完代替医療
有機化学

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10.1080/10286020.2018.1464561

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title = "A new ionone derivative from the leaves of Picrasma quassioides",

abstract = "Nigakialcohol A (1), as unusual cyclization ionone derivative, together with eight known ones (2–9), were isolated from the leaves of Picrasma quassioides (D. Don) Benn (Simaroubaceae). Their structures were elucidated by extensive spectroscopic analyses and comparison with literature data. Compound 2 showed a weak inhibitory effect on NO production at non-cytotoxic concentration (100 μM) with inhibitory rate of 59%, and thus it should be regarded as potential anti-inflammatory agents.",

keywords = "Picrasma quassioides, Simaroubaceae, anti-inflammatory, ionone derivatives",

author = "Chang Liu and Cheng, {Rong Rong} and Han, {Zhu zhen} and Yang, {Ying bo} and Yue Zhou and Li Yang and Wang, {Zheng Tao}",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2019",

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doi = "10.1080/10286020.2018.1464561",

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T1 - A new ionone derivative from the leaves of Picrasma quassioides

AU - Liu, Chang

AU - Cheng, Rong Rong

AU - Han, Zhu zhen

AU - Yang, Ying bo

AU - Zhou, Yue

AU - Yang, Li

AU - Wang, Zheng Tao

PY - 2019/7/3

Y1 - 2019/7/3

N2 - Nigakialcohol A (1), as unusual cyclization ionone derivative, together with eight known ones (2–9), were isolated from the leaves of Picrasma quassioides (D. Don) Benn (Simaroubaceae). Their structures were elucidated by extensive spectroscopic analyses and comparison with literature data. Compound 2 showed a weak inhibitory effect on NO production at non-cytotoxic concentration (100 μM) with inhibitory rate of 59%, and thus it should be regarded as potential anti-inflammatory agents.

AB - Nigakialcohol A (1), as unusual cyclization ionone derivative, together with eight known ones (2–9), were isolated from the leaves of Picrasma quassioides (D. Don) Benn (Simaroubaceae). Their structures were elucidated by extensive spectroscopic analyses and comparison with literature data. Compound 2 showed a weak inhibitory effect on NO production at non-cytotoxic concentration (100 μM) with inhibitory rate of 59%, and thus it should be regarded as potential anti-inflammatory agents.

KW - Picrasma quassioides

KW - Simaroubaceae

KW - anti-inflammatory

KW - ionone derivatives

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U2 - 10.1080/10286020.2018.1464561

DO - 10.1080/10286020.2018.1464561

M3 - 学術論文

C2 - 29717884

AN - SCOPUS:85046495113

SN - 1028-6020

VL - 21

SP - 652

EP - 658

JO - Journal of Asian Natural Products Research

JF - Journal of Asian Natural Products Research

IS - 7

ER -

A new ionone derivative from the leaves of Picrasma quassioides

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ASJC Scopus 主題領域

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