抄録
We synthesized a DNA-based fluorescent sensor, tailored to the recognition and signaling for hydrophobic guest molecules. The sensor molecule is made of three functional moieties, per-O-methylated β-cyclodextrin (per-Me-β-CD), DNA, and pyrene as guest-binding, dimerizing, and signaling ones, respectively. Addition of a porphyrin derivative as a hydrophobic guest molecule induced emission switching of the sensor molecule from monomer to excimer due to the DNA hybridization promoted by the host-guest binding.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 1132-1134 |
| ページ数 | 3 |
| ジャーナル | Bioconjugate Chemistry |
| 巻 | 19 |
| 号 | 6 |
| DOI | |
| 出版ステータス | 出版済み - 2008/06 |
ASJC Scopus 主題領域
- バイオテクノロジー
- バイオエンジニアリング
- 生体医工学
- 薬理学
- 薬科学
- 有機化学