TY - JOUR
T1 - A case of double cholangiolocellular carcinoma and hepatocellular carcinoma complicated with non-alcoholic steatohepatitis
AU - Kawano, Yutaka
AU - Kikuchi, Shohei
AU - Miyanishi, Koji
AU - Nagashima, Hiroyuki
AU - Hirakawa, Masahiro
AU - Tamura, Fumito
AU - Yoshida, Makoto
AU - Takahashi, Sho
AU - Takada, Kohichi
AU - Hayashi, Tsuyoshi
AU - Sato, Tsutomu
AU - Sato, Yasushi
AU - Takimoto, Risyu
AU - Kobune, Masayoshi
AU - Kawamoto, Masaki
AU - Mizuguchi, Toru
AU - Hirata, Koichi
AU - Hasegawa, Tadashi
AU - Kato, Junji
PY - 2012
Y1 - 2012
N2 - We report rare case of double cholangiolocellular carcinoma (CLC) and hepatocellular carcinoma complicated with non-alcoholic steatohepatitis (NASH). A 68-years old female with NASH was admitted to the hospital for examination and treatment of multiple hepatic tumors. Gd-EOB-DTPA enhanced MRI showed that tumor was located in segment 3, segment 4, and segment 6. The angiography and CT during angiography showed additional three tumors in segment 1 and segment 6. These tumors might be different tumor origin because of different imaging pattern. Operation was performed in segment 3 and 4, and RFA was performed in segment 1 and 6 because these tumors were diagnosed as hepatocellular carcinoma. Whitish tumor with clear margin which has no fibrous capsule was seen in tumor in segment 3. Pathologically, tumor in segment 3 showed CLC. Tumor in segment 4 was diagnosed as dysplastic nodule.
AB - We report rare case of double cholangiolocellular carcinoma (CLC) and hepatocellular carcinoma complicated with non-alcoholic steatohepatitis (NASH). A 68-years old female with NASH was admitted to the hospital for examination and treatment of multiple hepatic tumors. Gd-EOB-DTPA enhanced MRI showed that tumor was located in segment 3, segment 4, and segment 6. The angiography and CT during angiography showed additional three tumors in segment 1 and segment 6. These tumors might be different tumor origin because of different imaging pattern. Operation was performed in segment 3 and 4, and RFA was performed in segment 1 and 6 because these tumors were diagnosed as hepatocellular carcinoma. Whitish tumor with clear margin which has no fibrous capsule was seen in tumor in segment 3. Pathologically, tumor in segment 3 showed CLC. Tumor in segment 4 was diagnosed as dysplastic nodule.
KW - Cholangiolocellular carcinoma
KW - Hepatic progenitor cells
KW - Hepatocellular carcinoma
KW - Immunostaining
KW - Non-alcoholic steatohepatitis
UR - http://www.scopus.com/inward/record.url?scp=85051666105&partnerID=8YFLogxK
U2 - 10.2957/kanzo.53.615
DO - 10.2957/kanzo.53.615
M3 - 学術論文
AN - SCOPUS:85051666105
SN - 0451-4203
VL - 53
SP - 615
EP - 623
JO - Acta Hepatologica Japonica
JF - Acta Hepatologica Japonica
IS - 10
ER -