[3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon

Takenori Tomohiro; Akito Yamamoto; Yoko Tatsumi; Yasumaru Hatanaka

doi:10.1039/c3cc45780j

[3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon

Takenori Tomohiro^*, Akito Yamamoto, Yoko Tatsumi, Yasumaru Hatanaka

^*この論文の責任著者

生体認識化学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

抄録

A coumarin-fused diazirine photolabeling agent exhibited dramatic enhancement in fluorescence after cross-linking with the target protein. Fluorescence emission from the coumarin moiety was efficiently quenched by the diazirine group, and was then intensively recovered from photolysis treatment by irradiation with light at a wavelength of 365 nm.

本文言語	英語
ページ（範囲）	11551-11553
ページ数	3
ジャーナル	Chemical Communications
巻	49
号	98
DOI	https://doi.org/10.1039/c3cc45780j
出版ステータス	出版済み - 2013/11/14

ASJC Scopus 主題領域

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学一般
表面、皮膜および薄膜
金属および合金
材料化学

文献へのアクセス

10.1039/c3cc45780j

引用スタイル

@article{d246b40eaeb545859c1e1fb62c8c6bce,

title = "[3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon",

abstract = "A coumarin-fused diazirine photolabeling agent exhibited dramatic enhancement in fluorescence after cross-linking with the target protein. Fluorescence emission from the coumarin moiety was efficiently quenched by the diazirine group, and was then intensively recovered from photolysis treatment by irradiation with light at a wavelength of 365 nm.",

author = "Takenori Tomohiro and Akito Yamamoto and Yoko Tatsumi and Yasumaru Hatanaka",

year = "2013",

month = nov,

day = "14",

doi = "10.1039/c3cc45780j",

language = "英語",

volume = "49",

pages = "11551--11553",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "98",

}

TY - JOUR

T1 - [3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon

AU - Tomohiro, Takenori

AU - Yamamoto, Akito

AU - Tatsumi, Yoko

AU - Hatanaka, Yasumaru

PY - 2013/11/14

Y1 - 2013/11/14

N2 - A coumarin-fused diazirine photolabeling agent exhibited dramatic enhancement in fluorescence after cross-linking with the target protein. Fluorescence emission from the coumarin moiety was efficiently quenched by the diazirine group, and was then intensively recovered from photolysis treatment by irradiation with light at a wavelength of 365 nm.

AB - A coumarin-fused diazirine photolabeling agent exhibited dramatic enhancement in fluorescence after cross-linking with the target protein. Fluorescence emission from the coumarin moiety was efficiently quenched by the diazirine group, and was then intensively recovered from photolysis treatment by irradiation with light at a wavelength of 365 nm.

UR - http://www.scopus.com/inward/record.url?scp=84887871484&partnerID=8YFLogxK

U2 - 10.1039/c3cc45780j

DO - 10.1039/c3cc45780j

M3 - 学術論文

C2 - 24176947

AN - SCOPUS:84887871484

SN - 1359-7345

VL - 49

SP - 11551

EP - 11553

JO - Chemical Communications

JF - Chemical Communications

IS - 98

ER -

[3-(Trifluoromethyl)-3H-diazirin-3-yl]coumarin as a carbene-generating photocross-linker with masked fluorogenic beacon

抄録

ASJC Scopus 主題領域

文献へのアクセス

フィンガープリント

引用スタイル