Differential effects of small size gold nanoparticles on radiation and ultrasound-induce cell death

Therapy resistance and non-selectively are the major drawbacks associated with conventional anti-cancer therapies like radiation, etc. Gold nanoparticles(Au-NPs) effects can vary depending on the size and the applied physical stress. Therefore, we aim to create a targeted cancer cell death enhancement method, by utilizing the interaction between various sizes of Au-NPs and radiation/other physical stresses. The aim is also to develop selective cancer targeting method with less side effects on normal cells using optimized size or dose of Au-NPs for therapeutic application.