自然免疫受容体TLR7の活性阻害に基づく新規SLE治療薬の創出

Keyphrases

1. Innate Immune Receptors 100%
2. Systemic Lupus Erythematosus 50%
3. Toll-like Receptor 7 (TLR7) 50%
4. Therapeutic Agents 50%
5. Pharmacokinetic Stability 20%
6. Human Immune Cells 20%
7. Metabolic Stability 20%
8. Inhibitory Activity 20%
9. Small Molecule Inhibitors 10%
10. Structure-activity Relationship 10%
11. Biological Activity 10%
12. Structural Biology 10%
13. Derivative-based 10%

Pharmacology, Toxicology and Pharmaceutical Science

1. Systemic Lupus Erythematosus 100%
2. Receptor 100%
3. Toll Like Receptor 7 100%
4. Pharmacokinetics 20%
5. Structure Activity Relationship 20%
6. Mouse Model 20%
7. Biological Activity 20%