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慢性期脊髄損傷の薬物治療；骨格筋萎縮と軸索断裂を改善する生薬医薬品の開発研究
Tohda, Chihiro
(PI)
和漢医薬学総合研究所研究開発部門病態制御分野（神経機能学領域）
概要
フィンガープリント
研究成果
(15)
フィンガープリント
このプロジェクトで扱った研究トピックを検索します。これらのラベルは、プロジェクトの研究費/助成金に基づいて生成されます。これらがまとまってユニークなフィンガープリントを構成します。
並べ替え順
重み付け
アルファベット順
Keyphrases
5xFAD
67%
Acetylcholinesterase Inhibitors (AChEI)
10%
Acteoside
12%
Active Compounds
19%
Active Constituents
9%
Adverse Effects
8%
Aged Mice
12%
Alzheimer's Disease
73%
Alzheimer's Disease Model
71%
Alzheimer's Disease Pathology
6%
Alzheimer's Disease Patient
19%
Alzheimer's Disease Treatment
13%
Amyloid beta
12%
Anti-Alzheimer Drugs
9%
Anti-stress
9%
Aspartate Aminotransferase
12%
Astrocytes
7%
Astrogliosis
12%
Atrophy
16%
Axon
22%
Axonal Degeneration
55%
Axonal Density
8%
Axonal Growth
62%
B-type
12%
Bergmann Glia
12%
Binding Protein
10%
Biochemical Analysis
8%
Brain Penetration
12%
Brain Targeting
12%
Cast Immobilization
7%
Cathepsin L
12%
Cdc42
12%
Central Nervous System Injury
12%
Cerebral Cortex
14%
Chronic Spinal Cord Injury
37%
Circuit Remodeling
12%
Cistanche Tubulosa
24%
Co-immunoprecipitation (co-IP)
6%
Cognitive Function
42%
Cognitive Impairment
12%
Combined Treatment
12%
Conditioned Medium
9%
Cortical Neurons
18%
Corticogenesis
12%
Creatine kinase-MB (CK-MB)
12%
Cross-sectional Area
6%
Cultured Neurons
10%
Degradative Enzymes
12%
Dendrite
16%
Dendritic Atrophy
18%
Dendritic Growth
5%
Diosgenin
24%
Disease Model Mice
32%
Drug Affinity Responsive Target Stability
9%
Drynaria Fortunei
12%
Eleutherococcus Senticosus
24%
Eleutheroside B
9%
Endocytosis
7%
Enzyme Expression
12%
Expression Level
8%
Extracellular Heat Shock Proteins
14%
Flox
5%
Functional Recovery
16%
Glucose-regulated Protein 78 (GRP78)
12%
Growth Recovery
13%
Healthy Adults
24%
Healthy Volunteers
6%
Heat Shock Protein 70 (HSP70)
24%
Heat Shock Protein 90 (Hsp90)
14%
Hemopexin
12%
Heptapeptide
12%
Herbal Medicine
9%
Hindlimb
17%
Hindlimb Function
6%
Hippocampus
9%
Inflammation
8%
Intragroup
6%
Japanese Kampo Medicine
12%
Japanese Version
6%
Knockdown
10%
KO Mice
5%
Laennec
6%
Lateral Ventricle
6%
Leaf Extract
9%
Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS)
7%
Locomotive Syndrome
12%
M2 Microglia
12%
Mass Spectrometry Analysis
5%
Matrine
24%
Memory Ability
7%
Memory Deficits
30%
Memory Enhancement
12%
Memory Function
41%
Memory Impairment
42%
Memory Recovery
6%
Microglia
12%
Microglial M2 Polarization
24%
Mini-Mental State Examination
10%
Motor Function
35%
Motor Recovery
24%
Mouse Model
14%
Muscle Atrophy
16%
Muscle Mass
7%
Myofiber
6%
Myokines
12%
Myosin Heavy Chain (MyHC)
12%
Naringenin
20%
Natural Medicine
24%
Neural Circuits
12%
Neural Network
6%
Neurodegenerative Diseases
8%
Neurogenesis
12%
Neuroleukin
12%
Neuronal Network
10%
New Targets
7%
Object Recognition
8%
Object Recognition Memory
38%
Oral Administration
31%
Pathway Control
12%
Perirhinal Cortex
8%
Phase Transition
12%
Placebo-controlled
37%
Placenta Extract
6%
Placental Extract
17%
Polygalae Radix
24%
Porcine Placenta Extract
12%
Postsynaptic Density Protein 95 (PSD-95)
8%
Protective Effect
5%
Pyruvate Kinase Isoform M2
22%
Rac1
19%
Randomized Double-blind Crossover Study
12%
Randomized Double-blind Study
24%
RBANS
13%
Recombinant
13%
Seed Extract
6%
Sigma Phase
12%
Signaling Pathway
13%
Skeletal muscle
10%
Skeletal muscle Atrophy
18%
Skeletal muscle Cells
6%
Spinal Cord
7%
Spinal Cord Injury
50%
Spinal Cord Injury Model
7%
Stress Response
6%
Systematic Strategies
12%
Target Molecule
27%
Therapeutic Agents
13%
Transgenic Mouse Model
20%
Triceps Surae
8%
Trigonella Foenum-graecum Seeds
6%
Trigonelline
14%
Tubulin
10%
VER-155008
12%
Water Extract
18%
Wet Weight
6%
Neuroscience
Adverse Effect
13%
Alzheimer's Disease
100%
Amnesia
28%
Amyloid Protein
26%
Aspartate Aminotransferase
12%
Astrocyte
12%
Astrogliosis
12%
Axon
21%
Axonal Degeneration
54%
Blood Plasma
5%
Brain Function
6%
C-Fos
6%
Cathepsin L
12%
Cell Signaling
12%
Central Nervous System
18%
Cerebral Cortex
8%
Cognitive Disorders
8%
Cognitive Function
43%
Cognitive Function in Alzheimer's Disease
12%
Corticogenesis
12%
Cre Recombinase
5%
Creatine Kinase
12%
Crossover Study
12%
Dendrite
10%
Dentate Gyrus
6%
Diosgenin
24%
DNA Damage
6%
Early Growth Response Factor 1
12%
Eleutherococcus senticosus
12%
Endocytosis
7%
Enzyme Degradation
6%
Glia
12%
Glial Fibrillary Acidic Protein
10%
Glucose-6-Phosphate Isomerase
12%
Growth Cone
7%
Growth Disorder
6%
Heat Shock Protein 90
14%
Heptapeptide
12%
Hippocampus
6%
In Vivo
5%
Kampo Medicine (Drug)
12%
Matrine
24%
Memory
32%
Memory Disorder
16%
Microglia
23%
Naringenin
12%
Nerve Fiber Degeneration
54%
Neural Circuit
12%
Neural Network
6%
Perirhinal Cortex
11%
Placebo
24%
Protein Binding
10%
Protein Expression
12%
Pyruvate Kinase
12%
Recognition Memory
21%
Recovery from Spinal Cord Injury
13%
RNA-Seq
6%
Spinal Cord Injury
49%
Trigonelline
12%
Tubulin
12%
Vascular Endothelial Growth Factor
6%
Medicine and Dentistry
Acteoside
12%
Alzheimer's Disease
54%
Amyloid Protein
14%
Axon
6%
Cathepsin L
12%
Clinical Trial
6%
Cognition
28%
Cognitive Defect
14%
Cognitive Function in Alzheimer's Disease
12%
Disease Model
7%
Eleutherococcus senticosus
24%
Endocytosis
9%
Glucose-6-Phosphate Isomerase
12%
Growth Cone
7%
Heavy Meromyosin
12%
Hemopexin
12%
Hindlimb
16%
Hippocampus
8%
Homeopathy
6%
Kampo
12%
Lacunar Amnesia
16%
Medicine
15%
Memory
11%
Memory Disorder
17%
Methylpentynol
12%
Microglia
12%
Mini-Mental State Examination
9%
Mini-Mental State Examination Score
6%
Motor Performance
41%
Muscle Atrophy
16%
Myokine
12%
Nerve Cell Culture
9%
Nerve Fiber Degeneration
26%
Neutrophil Gelatinase Associated Lipocalin
5%
Oral Drug Administration
12%
Placebo
12%
Pyruvate Kinase
22%
Recovery from Spinal Cord Injury
13%
Secretion (Process)
14%
Skeletal Muscle
10%
Skeletal Muscle Atrophy
15%
Skeletal Muscle Cell
6%
Spinal Cord Injury
41%
Transgenic Mouse
12%
Triceps Surae Muscle
5%
Viscum Album Extract
6%