和漢医薬学総合研究所研究開発部門複雑系解析分野

WWP1 knockout in mice exacerbates obesity-related phenotypes in white adipose tissue but improves whole-body glucose metabolism

Hoshino, S., Kobayashi, M., Tagawa, R., Konno, R., Abe, T., Furuya, K., Miura, K., Wakasawa, H., Okita, N., Sudo, Y., Mizunoe, Y., Nakagawa, Y., Nakamura, T., Kawabe, H. & Higami, Y., 2020/03/01, In: FEBS Open Bio. 10, 3, p. 306-315 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

13 被引用数 (Scopus)

Wogonin, a Compound in Scutellaria baicalensis, Activates ATF4–FGF21 Signaling in Mouse Hepatocyte AML12 Cells

Yamada, Y., Saito, H., Araki, M., Tsuchimoto, Y., Muroi, S. I., Suzuki, K., Toume, K., Kim, J. D., Matsuzaka, T., Sone, H., Shimano, H. & Nakagawa, Y., 2022/10, In: Nutrients. 14, 19, 3920.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

4 被引用数 (Scopus)

Transgenic mice overexpressing nuclear SREBP-1c in pancreatic β-cells

Takahashi, A., Motomura, K., Kato, T., Yoshikawa, T., Nakagawa, Y., Yahagi, N., Sone, H., Suzuki, H., Toyoshima, H., Yamada, N. & Shimano, H., 2005/02, In: Diabetes. 54, 2, p. 492-499 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

84 被引用数 (Scopus)

Transcriptomic evaluation of pulmonary fibrosis-related genes: Utilization of transgenic mice with modifying p38 signal in the lungs

Matsuda, S., Kim, J. D., Sugiyama, F., Matsuo, Y., Ishida, J., Murata, K., Nakamura, K., Namiki, K., Sudo, T., Kuwaki, T., Hatano, M., Tatsumi, K., Fukamizu, A. & Kasuya, Y., 2020/09/02, In: International Journal of Molecular Sciences. 21, 18, p. 1-17 17 p., 6746.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

10 被引用数 (Scopus)

Transcriptomic changes involved in the dedifferentiation of myofibroblasts derived from the lung of a patient with idiopathic pulmonary fibrosis

Suzuki, K., Kim, J. D., Ugai, K., Matsuda, S., Mikami, H., Yoshioka, K., Ikari, J., Hatano, M., Fukamizu, A., Tatsumi, K. & Kasuya, Y., 2020/08, In: Molecular Medicine Reports. 22, 2, p. 1518-1526 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

15 被引用数 (Scopus)

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1

Ma, Y., Sekiya, M., Kainoh, K., Matsuda, T., Iwasaki, H., Osaki, Y., Sugano, Y., Suzuki, H., Takeuchi, Y., Miyamoto, T., Yahagi, N., Nakagawa, Y., Matsuzaka, T. & Shimano, H., 2020/03/05, In: Biochemical and Biophysical Research Communications. 523, 2, p. 354-360 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

The peroxisome proliferator-activated receptor α (PPARα) agonist pemafibrate protects against diet-induced obesity in mice

Araki, M., Nakagawa, Y., Oishi, A., Han, S. I., Wang, Y., Kumagai, K., Ohno, H., Mizunoe, Y., Iwasaki, H., Sekiya, M., Matsuzaka, T. & Shimano, H., 2018/07/23, In: International Journal of Molecular Sciences. 19, 7, 2148.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

65 被引用数 (Scopus)

The N-terminal sequence of murine PRMT5 variant 2 is required for Hsp70 interaction and CHIP ligase-mediated degradation

Lu, W., Kim, J. D., Tabara, S., Kwon, C., Mizukami, H., Kimura, K. & Fukamizu, A., 2019/07/05, In: Biochemical and Biophysical Research Communications. 514, 4, p. 1185-1191 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

Kato, M., Putta, S., Wang, M., Yuan, H., Lanting, L., Nair, I., Gunn, A., Nakagawa, Y., Shimano, H., Todorov, I., Rossi, J. J. & Natarajan, R., 2009/07/01, In: Nature Cell Biology. 11, 7, p. 881-889 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

537 被引用数 (Scopus)

Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment

Satou-Kobayashi, Y., Kim, J. D., Fukamizu, A. & Asashima, M., 2021/12, In: Scientific Reports. 11, 1, 14537.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages

Sone, H., Shimano, H., Shu, M., Nakakuki, M., Takahashi, A., Sakai, M., Sakamoto, Y., Yokoo, T., Matsuzaka, K., Okazaki, H., Nakagawa, Y., Iida, K. T., Suzuki, H., Toyoshima, H., Horiuchi, S. & Yamada, N., 2004/04/09, In: Biochemical and Biophysical Research Communications. 316, 3, p. 790-794 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

55 被引用数 (Scopus)

Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling

Nakagawa, Y., Kumagai, K., Han, S. I., Mizunoe, Y., Araki, M., Mizuno, S., Ohno, H., Matsuo, K., Yamada, Y., Kim, J. D., Miyamoto, T., Sekiya, M., Konishi, M., Itoh, N., Matsuzaka, T., Takahashi, S., Sone, H. & Shimano, H., 2021/06, In: FASEB Journal. 35, 6, e21663.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

SREBP-1-independent regulation of lipogenic gene expression in adipocytes

Sekiya, M., Yahagi, N., Matsuzaka, T., Takeuchi, Y., Nakagawa, Y., Takahashi, H., Okazaki, H., Iizuka, Y., Ohashi, K., Gotoda, T., Ishibashi, S., Nagai, R., Yamazaki, T., Kadowaki, T., Yamada, N., Osuga, J. I. & Shimano, H., 2007/07, In: Journal of Lipid Research. 48, 7, p. 1581-1591 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

116 被引用数 (Scopus)

Srebp-1c/Fgf21/Pgc-1α axis regulated by leptin signaling in adipocytes—possible mechanism of caloric restriction-associated metabolic remodeling of white adipose tissue

Kobayashi, M., Uta, S., Otsubo, M., Deguchi, Y., Tagawa, R., Mizunoe, Y., Nakagawa, Y., Shimano, H. & Higami, Y., 2020/07, In: Nutrients. 12, 7, p. 1-15 15 p., 2054.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

23 被引用数 (Scopus)

Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy

Osaki, Y., Nakagawa, Y., Miyahara, S., Iwasaki, H., Ishii, A., Matsuzaka, T., Kobayashi, K., Yatoh, S., Takahashi, A., Yahagi, N., Suzuki, H., Sone, H., Ohashi, K., Ishibashi, S., Yamada, N. & Shimano, H., 2015/10/23, In: Biochemical and Biophysical Research Communications. 466, 3, p. 536-540 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

72 被引用数 (Scopus)

Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca²⁺ Allostasis Toward β-Cell Failure

Motomura, K., Matsuzaka, T., Shichino, S., Ogawa, T., Pan, H., Nakajima, T., Asano, Y., Okayama, T., Takeuchi, T., Ohno, H., Han, S. I., Miyamoto, T., Takeuchi, Y., Sekiya, M., Sone, H., Yahagi, N., Nakagawa, Y., Oda, T., Ueha, S. & Ikeo, K. & 3 others, Ogura, A., Matsushima, K. & Shimano, H., 2024/01, In: Diabetes. 73, 1, p. 75-92 18 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice

Takei, K., Han, S. I., Murayama, Y., Satoh, A., Oikawa, F., Ohno, H., Osaki, Y., Matsuzaka, T., Sekiya, M., Iwasaki, H., Yatoh, S., Yahagi, N., Suzuki, H., Yamada, N., Nakagawa, Y. & Shimano, H., 2017/07, In: Journal of Diabetes Investigation. 8, 4, p. 446-452 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

39 被引用数 (Scopus)

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids

Han, S. I., Nakakuki, M., Nakagawa, Y., Wang, Y., Araki, M., Yamamoto, Y., Tokiwa, H., Takeda, H., Mizunoe, Y., Motomura, K., Ohno, H., Kainoh, K., Murayama, Y., Aita, Y., Takeuchi, Y., Osaki, Y., Miyamoto, T., Sekiya, M., Matsuzaka, T. & Yahagi, N. & 5 others, Sone, H., Daitoku, H., Sato, R., Kawano, H. & Shimano, H., 2023/11/01, In: PNAS nexus. 2, 11, 2.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats

Hasegawa, M., Toma-Fukai, S., Kim, J. D., Fukamizu, A. & Shimizu, T., 2014/05/21, In: FEBS Letters. 588, 10, p. 1942-1948 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

46 被引用数 (Scopus)

Prolonged caloric restriction ameliorates age-related atrophy in slow and fast muscle fibers of rat soleus muscle

Mizunoe, Y., Kobayashi, M., Saito, H., Goto, A., Migitaka, R., Miura, K., Okita, N., Sudo, Y., Tagawa, R., Yoshida, M., Umemori, A., Nakagawa, Y., Shimano, H. & Higami, Y., 2021/10/15, In: Experimental Gerontology. 154, 111519.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

PRMT1 Deficiency in Mouse Juvenile Heart Induces Dilated Cardiomyopathy and Reveals Cryptic Alternative Splicing Products

Murata, K., Lu, W., Hashimoto, M., Ono, N., Muratani, M., Nishikata, K., Kim, J. D., Ebihara, S., Ishida, J. & Fukamizu, A., 2018/10/26, In: iScience. 8, p. 200-213 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

30 被引用数 (Scopus)

Predictive ability of current machine learning algorithms for type 2 diabetes mellitus: A meta-analysis

Kodama, S., Fujihara, K., Horikawa, C., Kitazawa, M., Iwanaga, M., Kato, K., Watanabe, K., Nakagawa, Y., Matsuzaka, T., Shimano, H. & Sone, H., 2022/05, In: Journal of Diabetes Investigation. 13, 5, p. 900-908 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

22 被引用数 (Scopus)

Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit

Takeuchi, Y., Yahagi, N., Izumida, Y., Nishi, M., Kubota, M., Teraoka, Y., Yamamoto, T., Matsuzaka, T., Nakagawa, Y., Sekiya, M., Iizuka, Y., Ohashi, K., Osuga, J. I., Gotoda, T., Ishibashi, S., Itaka, K., Kataoka, K., Nagai, R., Yamada, N. & Kadowaki, T. & 1 others, Shimano, H., 2010/04/09, In: Journal of Biological Chemistry. 285, 15, p. 11681-11691 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

123 被引用数 (Scopus)

Pathophysiological roles of stress-activated protein kinases in pulmonary fibrosis

Kasuya, Y., Kim, J. D., Hatano, M., Tatsumi, K. & Matsuda, S., 2021/06/01, In: International Journal of Molecular Sciences. 22, 11, 6041.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

29 被引用数 (Scopus)

Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets

Kato, T., Shimano, H., Yamamoto, T., Ishikawa, M., Kumadaki, S., Matsuzaka, T., Nakagawa, Y., Yahagi, N., Nakakuki, M., Hasty, A. H., Takeuchi, Y., Kobayashi, K., Takahashi, A., Yatoh, S., Suzuki, H., Sone, H. & Yamada, N., 2008/09, In: Diabetes. 57, 9, p. 2382-2392 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

85 被引用数 (Scopus)

p53 Involvement in the pathogenesis of fatty liver disease

Yahagi, N., Shimano, H., Matsuzaka, T., Sekiya, M., Najima, Y., Okazaki, S., Okazaki, H., Tamura, Y., Iizuka, Y., Inoue, N., Nakagawa, Y., Takeuchi, Y., Ohashi, K., Harada, K., Gotoda, T., Nagai, R., Kadowaki, T., Ishibashi, S., Osuga, J. I. & Yamada, N., 2004/05/14, In: Journal of Biological Chemistry. 279, 20, p. 20571-20575 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

109 被引用数 (Scopus)

p53 activation in adipocytes of obese mice

Yahagi, N., Shimano, H., Matsuzaka, T., Najima, Y., Sekiya, M., Nakagawa, Y., Ide, T., Tomita, S., Okazaki, H., Tamura, Y., Iizuka, Y., Ohashi, K., Gotoda, T., Nagai, R., Kimura, S., Ishibashi, S., Osuga, J. I. & Yamada, N., 2003/07/11, In: Journal of Biological Chemistry. 278, 28, p. 25395-25400 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

195 被引用数 (Scopus)

Oxysterol binding protein regulates the resolution of TLR-induced cytokine production in macrophages

Diercks, A. H., Podolskaia, I. S., Murray, T. A., Jahn, A. N., Mai, D., Liu, D., Amon, L. M., Nakagawa, Y., Shimano, H., Aderem, A. & Gold, E. S., 2024/08/13, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 33, e2406492121.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity

Saito, K., Sekiya, M., Kainoh, K., Yoshino, R., Hayashi, A., Han, S. I., Araki, M., Ohno, H., Takeuchi, Y., Tsuyuzaki, T., Yamazaki, D., Wanpei, C., Hada, L., Watanabe, S., Paramita Adi Putri, P. I., Murayama, Y., Sugano, Y., Osaki, Y., Iwasaki, H. & Yahagi, N. & 4 others, Suzuki, H., Miyamoto, T., Matsuzaka, T. & Shimano, H., 2023/07, In: Journal of Biological Chemistry. 299, 7, 104890.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

8 被引用数 (Scopus)

Multi-omics analysis of right ventricles in rat models of pulmonary arterial hypertension: Consideration of mitochondrial biogenesis by chrysin

Kobayashi, T., Kim, J. D., Naito, A., Yanagisawa, A., Jujo-Sanada, T., Kasuya, Y., Nakagawa, Y., Sakao, S., Tatsumi, K. & Suzuki, T., 2022/05, In: International Journal of Molecular Medicine. 49, 5, 5124.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

10 被引用数 (Scopus)

Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice

Okajima, Y., Matsuzaka, T., Miyazaki, S., Motomura, K., Ohno, H., Sharma, R., Shimura, T., Istiqamah, N., Han, S. I., Mizunoe, Y., Osaki, Y., Iwasaki, H., Yatoh, S., Suzuki, H., Sone, H., Miyamoto, T., Aita, Y., Takeuchi, Y., Sekiya, M. & Yahagi, N. & 3 others, Nakagawa, Y., Tomita, T. & Shimano, H., 2022/04/01, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1868, 4, 166339.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions

Nozaki, Y., Kobayashi, M., Fukuoh, T., Ishimatsu, M., Narita, T., Taki, K., Hirao, Y., Ayabe, S., Yokoyama, M., Otani, Y., Mizunoe, Y., Matsumoto, M., Ohno, N., Kaifu, T., Okazaki, S., Goitsuka, R., Nakagawa, Y., Shimano, H., Iwakura, Y. & Higami, Y., 2025/12, In: Scientific Reports. 15, 1, 12839.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Macrophage SREBP1 regulates skeletal muscle regeneration

Oishi, Y., Koike, H., Kumagami, N., Nakagawa, Y., Araki, M., Taketomi, Y., Miki, Y., Matsuda, S., Matsuzaka, T., Ozawa, H., Shimano, H., Murakami, M. & Manabe, I., 2023, In: Frontiers in Immunology. 14, 1251784.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Loss of PRMT1 in the central nervous system (CNS) induces reactive astrocytes and microglia during postnatal brain development

Hashimoto, M., Kumabe, A., Kim, J. D., Murata, K., Sekizar, S., Williams, A., Lu, W., Ishida, J., Nakagawa, T., Endo, M., Minami, Y. & Fukamizu, A., 2021/03, In: Journal of Neurochemistry. 156, 6, p. 834-847 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (Scopus)

Lipid synthetic transcription factor SREBP-1a activates p21 ^WAF1/CIP1, a universal cyclin-dependent kinase inhibitor

Inoue, N., Shimano, H., Nakakuki, M., Matsuzaka, T., Nakagawa, Y., Yamamoto, T., Sato, R., Takahashi, A., Sone, H., Yahagi, N., Suzuki, H., Toyoshima, H. & Yamada, N., 2005/10, In: Molecular and cellular biology. 25, 20, p. 8938-8947 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

55 被引用数 (Scopus)

Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver

Ehara, T., Kamei, Y., Yuan, X., Takahashi, M., Kanai, S., Tamura, E., Tsujimoto, K., Tamiya, T., Nakagawa, Y., Shimano, H., Takai-Igarashi, T., Hatada, I., Suganami, T., Hashimoto, K. & Ogawa, Y., 2015/03, In: Diabetes. 64, 3, p. 775-784 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

53 被引用数 (Scopus)

KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting

Takeuchi, Y., Yahagi, N., Aita, Y., Murayama, Y., Sawada, Y., Piao, X., Toya, N., Oya, Y., Shikama, A., Takarada, A., Masuda, Y., Nishi, M., Kubota, M., Izumida, Y., Yamamoto, T., Sekiya, M., Matsuzaka, T., Nakagawa, Y., Urayama, O. & Kawakami, Y. & 10 others, Iizuka, Y., Gotoda, T., Itaka, K., Kataoka, K., Nagai, R., Kadowaki, T., Yamada, N., Lu, Y., Jain, M. K. & Shimano, H., 2016/08/30, In: Cell Reports. 16, 9, p. 2373-2386 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

74 被引用数 (Scopus)

KDM5D-mediated H3K4 demethylation is required for sexually dimorphic gene expression in mouse embryonic fibroblasts

Mizukami, H., Kim, J. D., Tabara, S., Lu, W., Kwon, C., Nakashima, M. & Fukamizu, A., 2019/04/01, In: Journal of Biochemistry. 165, 4, p. 335-342 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice

Watanabe, Y., Fujisaka, S., Morinaga, Y., Watanabe, S., Nawaz, A., Hatta, H., Kado, T., Nishimura, A., Bilal, M., Aslam, M. R., Honda, K., Nakagawa, Y., Softic, S., Hirabayashi, K., Nakagawa, T., Nagai, Y. & Tobe, K., 2023/11, In: Molecular Metabolism. 77, 101797.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

19 被引用数 (Scopus)

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress

Lerner, A. G., Upton, J. P., Praveen, P. V. K., Ghosh, R., Nakagawa, Y., Igbaria, A., Shen, S., Nguyen, V., Backes, B. J., Heiman, M., Heintz, N., Greengard, P., Hui, S., Tang, Q., Trusina, A., Oakes, S. A. & Papa, F. R., 2012/08/08, In: Cell Metabolism. 16, 2, p. 250-264 15 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

720 被引用数 (Scopus)

In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression

Takeuchi, Y., Yahagi, N., Nakagawa, Y., Matsuzaka, T., Shimizu, R., Sekiya, M., Iizuka, Y., Ohashi, K., Gotoda, T., Yamamoto, M., Nagai, R., Kadowaki, T., Yamada, N., Osuga, J. I. & Shimano, H., 2007/11/16, In: Biochemical and Biophysical Research Communications. 363, 2, p. 329-335 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

17 被引用数 (Scopus)

Impact of the SIK3 pathway inhibition on osteoclast differentiation via oxidative phosphorylation

Kamei, K., Yahara, Y., Kim, J.-D., Tsuji, M., Iwasaki, M., Takemori, H., Seki, S., Makino, H., Futakawa, H., Hirokawa, T., Tung, N. T. C., Nakagawa, T. & Kawaguchi, Y., 2024/07/20, In: Journal of Bone and Mineral Research. 39, 9, p. 1340 1355 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages

Okazaki, H., Igarashi, M., Nishi, M., Sekiya, M., Tajima, M., Takase, S., Takanashi, M., Ohta, K., Tamura, Y., Okazaki, S., Yahagi, N., Ohashi, K., Amemiya-Kudo, M., Nakagawa, Y., Nagai, R., Kadowaki, T., Osuga, J. I. & Ishibashi, S., 2008/11/28, In: Journal of Biological Chemistry. 283, 48, p. 33357-33364 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

90 被引用数 (Scopus)

Identification of herbal drug extracts that promote growth of Akkermansia muciniphila in high-fat diet fed mice

Fujisaka, S., Watanabe, Y., Toume, K., Morinaga, Y., Nawaz, A., Kado, T., Nishimura, A., Bilal, M., Aslam, M. R., Igarashi, Y., Nakagawa, Y. & Tobe, K., 2024/07, In: Diabetology International. 15, 3, p. 495-506 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

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Histamine receptor agonist alleviates severe cardiorenal damages by eliciting anti-inflammatory programming

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研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

16 被引用数 (Scopus)

High-power laser experiment forming a supercritical collisionless shock in a magnetized uniform plasma at rest

寄稿の翻訳タイトル: High-power laser experiment forming a supercritical collisionless shock in a magnetized uniform plasma at restYamazaki, R., Matsukiyo, S., Morita, T., Tanaka, S. J., Umeda, T., Aihara, K., Edamoto, M., Egashira, S., Hatsuyama, R., Higuchi, T., Hihara, T., Horie, Y., Hoshino, M., Ishii, A., Ishizaka, N., Itadani, Y., Izumi, T., Kambayashi, S., Kakuchi, S. & Katsuki, N. & 34 others, Kawamura, R., Kawamura, Y., Kisaka, S., Kojima, T., Konuma, A., Kumar, R., Minami, T., Miyata, I., Moritaka, T., Murakami, Y., Nagashima, K., Nakagawa, Y., Nishimoto, T., Nishioka, Y., Ohira, Y., Ohnishi, N., Ota, M., Ozaki, N., Sano, T., Sakai, K., Sei, S., Shiota, J., Shoji, Y., Sugiyama, K., Suzuki, D., Takagi, M., Toda, H., Tomita, S., Tomiya, S., Yoneda, H., Takezaki, T., Tomita, K., Kuramitsu, Y. & Sakawa, Y., 2022/02, In: Physical Review E. 105, p. 10883-

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

15 被引用数 (Scopus)

High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding

Najima, Y., Yahagi, N., Takeuchi, Y., Matsuzaka, T., Sekiya, M., Nakagawa, Y., Amemiya-Kudo, M., Okazaki, H., Okazaki, S., Tamura, Y., Iizuka, Y., Ohashi, K., Harada, K., Gotoda, T., Nagai, R., Kadowaki, T., Ishibashi, S., Yamada, N., Osuga, J. I. & Shimano, H., 2005/07/29, In: Journal of Biological Chemistry. 280, 30, p. 27523-27532 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

40 被引用数 (Scopus)

Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease

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研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

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Hepatic ketone body regulation of renal gluconeogenesis

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研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Hepatic CREB3L3 controls whole-body energy homeostasis and improves obesity and diabetes

Nakagawa, Y., Satoh, A., Yabe, S., Furusawa, M., Tokushige, N., Tezuka, H., Mikami, M., Iwata, W., Shingyouchi, A., Matsuzaka, T., Kiwata, S., Fujimoto, Y., Shimizu, H., Danno, H., Yamamoto, T., Ishii, K., Karasawa, T., Takeuchi, Y., Iwasaki, H. & Shimada, M. & 11 others, Kawakami, Y., Urayama, O., Sone, H., Takekoshi, K., Kobayashi, K., Yatoh, S., Takahashi, A., Yahagi, N., Suzuki, H., Yamada, N. & Shimano, H., 2014/12/01, In: Endocrinology. 155, 12, p. 4706-4719 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

55 被引用数 (Scopus)

和漢医薬学総合研究所研究開発部門複雑系解析分野

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