Synthetic studies on pyrroloindolizidine skeleton based on gold-catalyzed hydroamination-enamine cyclization-ring-closing metathesis strategy

Kenji Sugimoto, Natsumi Matsuo, Daisuke Tominaga, Yuji Matsuya*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A pyrroloindolizidine skeleton, which is observed in myrmicarin alkaloids isolated from African ant, is highly unique, oligocyclic indolizidine derivative. We describe here an attempt on a synthesis of a pyrroloindolizidine skeleton with our originally developed gold-catalyzed cascade reaction and a newly developed synthetic route for the skeleton via gold-catalyzed hydroamination-enamine cyclization-ring-closing metathesis.

Original languageEnglish
Pages (from-to)875-890
Number of pages16
JournalHeterocycles
Volume99
Issue number2
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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