Synthesis of natural (S)-(-)-Tulipalin B starting from L-malic acid as a chiral pool

Osamu Muraoka*, Naoki Toyooka, Yumiko Ohshima, Norihiko Narita, Takefumi Momose

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The naturally occurring α-methylene-γ-lactone Tulipalin B (2) was synthesized enantioselectively starting from L-malic acid as a chiral pool in 15% overall yield.

Original languageEnglish
Pages (from-to)269-272
Number of pages4
JournalHeterocycles
Volume29
Issue number2
DOIs
StatePublished - 1989/02/01

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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