Simulation for population pharmacodynamic analysis of dose-ranging trials: Usefulness of the mixture model analysis for detecting nonresponders

Takeshi Shiiki, Yukiya Hashimoto, Ken Ichi Inui

Research output: Contribution to journalArticlepeer-review

5 Scopus citations
Original languageEnglish
Pages (from-to)909-913
Number of pages5
JournalPharmaceutical Research
Volume19
Issue number6
DOIs
StatePublished - 2002

Keywords

  • Dose-ranging trial
  • Mixture model
  • NONMEM
  • Non-responder
  • Population pharmacodynamics

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Organic Chemistry
  • Pharmacology (medical)

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