Regional contributions of D-serine to Alzheimer’s disease pathology in male App^{NL–G–F/NL–G–F} mice

Keyphrases

• Gene Knockout 100%
• Alzheimer's Disease Pathology 100%
• Regional Contribution 100%
• Serine Racemase 50%
• Hippocampal CA1 Region 40%
• N-methyl-D-aspartate Receptor (NMDAR) 30%
• Neurotoxicity 20%
• Alzheimer's Disease 20%
• Neurodegeneration 20%
• Neuronal Loss 20%
• Retrosplenial Cortex 20%
• Neurodegenerative Processes 20%
• Wild Mice 10%
• Expression Level 10%
• Dysregulation 10%
• Mammalian Brain 10%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 10%
• Drinking Water 10%
• Age-matched 10%
• Receptor-mediated 10%
• Effective Strategies 10%
• Neuronal Death 10%
• Alzheimer's Disease Model 10%
• Amyloid Pathology 10%
• Amino Acid Content 10%
• Reactive Astrogliosis 10%
• Neuropathology 10%
• Co-agonist 10%
• Neuronal Density 10%
• Brain Amino Acid 10%
• Astrogliosis 10%

Neuroscience

• Alzheimer's Disease 100%
• Serine 100%
• Gene Knockin 90%
• Serine Racemase 45%
• Aspartic Acid 27%
• Receptor 27%
• Amino Acid 18%
• Neurodegeneration 18%
• Astrogliosis 18%
• Excitotoxicity 18%
• Neurodegenerative Process 18%
• Mass Spectrometry 9%
• Agonist 9%
• Amyloid Protein 9%
• Neuronal Cell Death 9%