Ovarian squamous cell carcinoma which metastasized 8 years after cervical conization for early microinvasive cervical cancer: A case report

Takao Hidaka*, Akitoshi Nakashima, Toru Hasegawa, Kazuhiro Nomoto, Shin Ishizawa, Koichi Tsuneyama, Yasuo Takano, Shigeru Saito

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Squamous cell cervical carcinoma that metastasized to the ovary is common in patients with bulky tumors or locally advanced disease; however, ovarian squamous cell carcinoma that metastasized after cervical conization surgery for early microinvasive uterine cervical carcinoma is very rare. We present a case of ovarian squamous cell carcinoma that metastasized 8 years after cervical conization surgery for early microinvasive cervical carcinoma. She had no sign of recurrence in the uterine cervix. We detected human papillomavirus type 16 DNA in both cervical tissue and ovarian tissue, suggesting that ovarian squamous cell carcinoma is derived from microinvasive cervical cancer. Although there are very few cases of early microinvasive squamous cell carcinoma that metastasized to the ovary with delayed recurrence, we should pay attention strictly not only to the cervical condition but also to the ovarian condition on regular post-operative follow-up.

Original languageEnglish
Article numberhyr041
Pages (from-to)807-810
Number of pages4
JournalJapanese Journal of Clinical Oncology
Volume41
Issue number6
DOIs
StatePublished - 2011/06

Keywords

  • Cervical conization
  • Human papillomavirus
  • Microinvasive cervical carcinoma
  • Ovarian metastasis
  • Squamous cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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