N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

J. Désiré*, M. Mondon, N. Fontelle, S. Nakagawa, Y. Hirokami, I. Adachi, R. Iwaki, G. W.J. Fleet, D. S. Alonzi, G. Twigg, T. D. Butters, J. Bertrand, V. Cendret, F. Becq, C. Norez, J. Marrot, A. Kato, Y. Blériot

*Corresponding author for this work

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Chemistry

Pharmacology, Toxicology and Pharmaceutical Science