Lipase-mediated preparation of optically active isomers of Rosaphen®

Masashi Kawasaki; Naoki Toyooka; Tomoki Saka; Michimasa Goto; Yuji Matsuya; Tadashi Kometani

doi:10.1016/j.molcatb.2010.07.019

Lipase-mediated preparation of optically active isomers of Rosaphen®

Masashi Kawasaki^*, Naoki Toyooka, Tomoki Saka, Michimasa Goto, Yuji Matsuya, Tadashi Kometani

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The optically active isomers of Rosaphen® (RS)-1 were synthesized from the chiral intermediate prepared by lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are reported.

Original language	English
Pages (from-to)	135-142
Number of pages	8
Journal	Journal of Molecular Catalysis B: Enzymatic
Volume	67
Issue number	1-2
DOIs	https://doi.org/10.1016/j.molcatb.2010.07.019
State	Published - 2010/11

Keywords

Asymmetric synthesis
Fragrance
Lipase

ASJC Scopus subject areas

Catalysis
Bioengineering
Biochemistry
Process Chemistry and Technology

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10.1016/j.molcatb.2010.07.019

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title = "Lipase-mediated preparation of optically active isomers of Rosaphen{\textregistered}",

abstract = "The optically active isomers of Rosaphen{\textregistered} (RS)-1 were synthesized from the chiral intermediate prepared by lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are reported.",

keywords = "Asymmetric synthesis, Fragrance, Lipase",

author = "Masashi Kawasaki and Naoki Toyooka and Tomoki Saka and Michimasa Goto and Yuji Matsuya and Tadashi Kometani",

year = "2010",

month = nov,

doi = "10.1016/j.molcatb.2010.07.019",

language = "英語",

volume = "67",

pages = "135--142",

journal = "Journal of Molecular Catalysis B: Enzymatic",

issn = "1381-1177",

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number = "1-2",

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TY - JOUR

T1 - Lipase-mediated preparation of optically active isomers of Rosaphen®

AU - Kawasaki, Masashi

AU - Toyooka, Naoki

AU - Saka, Tomoki

AU - Goto, Michimasa

AU - Matsuya, Yuji

AU - Kometani, Tadashi

PY - 2010/11

Y1 - 2010/11

N2 - The optically active isomers of Rosaphen® (RS)-1 were synthesized from the chiral intermediate prepared by lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are reported.

AB - The optically active isomers of Rosaphen® (RS)-1 were synthesized from the chiral intermediate prepared by lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are reported.

KW - Asymmetric synthesis

KW - Fragrance

KW - Lipase

UR - http://www.scopus.com/inward/record.url?scp=77956893668&partnerID=8YFLogxK

U2 - 10.1016/j.molcatb.2010.07.019

DO - 10.1016/j.molcatb.2010.07.019

M3 - 学術論文

AN - SCOPUS:77956893668

SN - 1381-1177

VL - 67

SP - 135

EP - 142

JO - Journal of Molecular Catalysis B: Enzymatic

JF - Journal of Molecular Catalysis B: Enzymatic

IS - 1-2

ER -

Lipase-mediated preparation of optically active isomers of Rosaphen®

Abstract

Keywords

ASJC Scopus subject areas

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