Eight stereoisomers of homonojirimycin from d -mannose

Gabriel M.J. Lenagh-Snow; Sarah F. Jenkinson; Scott J. Newberry; Atsushi Kato; Shinpei Nakagawa; Isao Adachi; Mark R. Wormald; Akihide Yoshihara; Kenji Morimoto; Kazuya Akimitsu; Ken Izumori; George W.J. Fleet

doi:10.1021/ol3005744

Eight stereoisomers of homonojirimycin from d -mannose

Gabriel M.J. Lenagh-Snow, Sarah F. Jenkinson, Scott J. Newberry, Atsushi Kato, Shinpei Nakagawa, Isao Adachi, Mark R. Wormald, Akihide Yoshihara, Kenji Morimoto, Kazuya Akimitsu, Ken Izumori, George W.J. Fleet^*

^*Corresponding author for this work

Hospital Pharmacy

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Although there are 32 6-azidoheptitols, there are only 16 homonojirimycin (HNJ) stereoisomers. Two epimeric azidoalditols derived from d-mannose allow the synthesis in water of eight stereoisomers of HNJ.

Original language	English
Pages (from-to)	2050-2053
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	8
DOIs	https://doi.org/10.1021/ol3005744
State	Published - 2012/04/20

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Eight stereoisomers of homonojirimycin from d -mannose",

abstract = "Although there are 32 6-azidoheptitols, there are only 16 homonojirimycin (HNJ) stereoisomers. Two epimeric azidoalditols derived from d-mannose allow the synthesis in water of eight stereoisomers of HNJ.",

author = "Lenagh-Snow, {Gabriel M.J.} and Jenkinson, {Sarah F.} and Newberry, {Scott J.} and Atsushi Kato and Shinpei Nakagawa and Isao Adachi and Wormald, {Mark R.} and Akihide Yoshihara and Kenji Morimoto and Kazuya Akimitsu and Ken Izumori and Fleet, {George W.J.}",

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T1 - Eight stereoisomers of homonojirimycin from d -mannose

AU - Lenagh-Snow, Gabriel M.J.

AU - Jenkinson, Sarah F.

AU - Newberry, Scott J.

AU - Kato, Atsushi

AU - Nakagawa, Shinpei

AU - Adachi, Isao

AU - Wormald, Mark R.

AU - Yoshihara, Akihide

AU - Morimoto, Kenji

AU - Akimitsu, Kazuya

AU - Izumori, Ken

AU - Fleet, George W.J.

PY - 2012/4/20

Y1 - 2012/4/20

N2 - Although there are 32 6-azidoheptitols, there are only 16 homonojirimycin (HNJ) stereoisomers. Two epimeric azidoalditols derived from d-mannose allow the synthesis in water of eight stereoisomers of HNJ.

AB - Although there are 32 6-azidoheptitols, there are only 16 homonojirimycin (HNJ) stereoisomers. Two epimeric azidoalditols derived from d-mannose allow the synthesis in water of eight stereoisomers of HNJ.

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U2 - 10.1021/ol3005744

DO - 10.1021/ol3005744

M3 - 学術論文

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SN - 1523-7060

VL - 14

SP - 2050

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JO - Organic Letters

JF - Organic Letters

IS - 8

ER -

Eight stereoisomers of homonojirimycin from d -mannose

Abstract

ASJC Scopus subject areas

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