Asymmetric twin-ring differentiation by lipase-catalyzed enantiotoposelective reaction of the ring-crossed meso glycol: Asymmetric synthesis of a highly functionalized piperidine from the conjoined twin piperidine system

Takefumi Momose; Naoki Toyooka; Makoto Jin

doi:10.1016/S0040-4039(00)79101-5

Asymmetric twin-ring differentiation by lipase-catalyzed enantiotoposelective reaction of the ring-crossed meso glycol: Asymmetric synthesis of a highly functionalized piperidine from the conjoined twin piperidine system

Takefumi Momose^*, Naoki Toyooka, Makoto Jin

^*Corresponding author for this work

Life Sciences and Bioengineering

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Both enantiomers of the homochiral 3-oxygenated 2,6-cis-disubstituted piperidine 1 were synyhesized by starting with lipase-catalyzed transesterification or hydrolysis of the meso glycol or its diacetate in the conjoined twin piperidine system.

Original language	English
Pages (from-to)	5389-5390
Number of pages	2
Journal	Tetrahedron Letters
Volume	33
Issue number	37
DOIs	https://doi.org/10.1016/S0040-4039(00)79101-5
State	Published - 1992/09/08

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Asymmetric twin-ring differentiation by lipase-catalyzed enantiotoposelective reaction of the ring-crossed meso glycol: Asymmetric synthesis of a highly functionalized piperidine from the conjoined twin piperidine system",

abstract = "Both enantiomers of the homochiral 3-oxygenated 2,6-cis-disubstituted piperidine 1 were synyhesized by starting with lipase-catalyzed transesterification or hydrolysis of the meso glycol or its diacetate in the conjoined twin piperidine system.",

author = "Takefumi Momose and Naoki Toyooka and Makoto Jin",

year = "1992",

month = sep,

day = "8",

doi = "10.1016/S0040-4039(00)79101-5",

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volume = "33",

pages = "5389--5390",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "37",

}

Asymmetric twin-ring differentiation by lipase-catalyzed enantiotoposelective reaction of the ring-crossed meso glycol: Asymmetric synthesis of a highly functionalized piperidine from the conjoined twin piperidine system. / Momose, Takefumi; Toyooka, Naoki; Jin, Makoto.
In: Tetrahedron Letters, Vol. 33, No. 37, 08.09.1992, p. 5389-5390.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Asymmetric twin-ring differentiation by lipase-catalyzed enantiotoposelective reaction of the ring-crossed meso glycol

T2 - Asymmetric synthesis of a highly functionalized piperidine from the conjoined twin piperidine system

AU - Momose, Takefumi

AU - Toyooka, Naoki

AU - Jin, Makoto

PY - 1992/9/8

Y1 - 1992/9/8

N2 - Both enantiomers of the homochiral 3-oxygenated 2,6-cis-disubstituted piperidine 1 were synyhesized by starting with lipase-catalyzed transesterification or hydrolysis of the meso glycol or its diacetate in the conjoined twin piperidine system.

AB - Both enantiomers of the homochiral 3-oxygenated 2,6-cis-disubstituted piperidine 1 were synyhesized by starting with lipase-catalyzed transesterification or hydrolysis of the meso glycol or its diacetate in the conjoined twin piperidine system.

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DO - 10.1016/S0040-4039(00)79101-5

M3 - 学術論文

AN - SCOPUS:0026706987

SN - 0040-4039

VL - 33

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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