Abstract
The phytochemical investigation of the MeOH extract from fruits of Kotschya strigosa using repeated normal and reversed-phase column chromatography and Sephadex LH-20 chromatography led to the isolation and characterization of a new isoflavanol, named kotstrigoisoflavanol (1), together with three known compounds, diosmetin (2), β-sitosterol (3), and the 3-O-β-d-glucopyranoside of β-sitosterol (4). The antioxidant activity of crude extract, 1, and 2 was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPḢ) method. The crude extract (IC50 61.7 ± 0.2 μg/ml) and 2 (IC50 70.2 ± 0.1 μg/ml) showed moderate antioxidant activities, while 1 was weakly active (IC50 153.1 ± 0.1 μg/ml), as compared with the standard reference l-ascorbic acid (IC50 21.9 ± 0.0 μg/ml).
Original language | English |
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Pages (from-to) | 321-324 |
Number of pages | 4 |
Journal | Helvetica Chimica Acta |
Volume | 99 |
Issue number | 4 |
DOIs | |
State | Published - 2016/04/01 |
Keywords
- Antioxidant activity
- Isoflavanol
- Kotschya strigosa
- Kotstrigoisoflavanol
ASJC Scopus subject areas
- Catalysis
- Biochemistry
- Drug Discovery
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry