A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review

Masatoshi Kawataka; Toshiki Kido; Reina Tsuda; Takafumi Onose; Ryoko Asano; Miho Yamazaki; Naonori Sugishita; Hiroyuki Hounoki; Toshiko Kakiuchi; Koichiro Shinoda; Kazuyuki Tobe

doi:10.1155/2021/4416072

A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review

Masatoshi Kawataka, Toshiki Kido, Reina Tsuda, Takafumi Onose, Ryoko Asano, Miho Yamazaki, Naonori Sugishita, Hiroyuki Hounoki, Toshiko Kakiuchi, Koichiro Shinoda, Kazuyuki Tobe

University of Toyama

Research output: Contribution to journal › Article › peer-review

Abstract

A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases.

Original language	English
Pages (from-to)	4416072
Journal	Case reports in rheumatology
Volume	2021
DOIs	https://doi.org/10.1155/2021/4416072
State	Published - 2021/08/20

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title = "A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review",

abstract = "A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases.",

author = "Masatoshi Kawataka and Toshiki Kido and Reina Tsuda and Takafumi Onose and Ryoko Asano and Miho Yamazaki and Naonori Sugishita and Hiroyuki Hounoki and Toshiko Kakiuchi and Koichiro Shinoda and Kazuyuki Tobe",

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year = "2021",

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day = "20",

doi = "10.1155/2021/4416072",

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TY - JOUR

T1 - A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms

T2 - A Case-Based Review

AU - Kawataka, Masatoshi

AU - Kido, Toshiki

AU - Tsuda, Reina

AU - Onose, Takafumi

AU - Asano, Ryoko

AU - Yamazaki, Miho

AU - Sugishita, Naonori

AU - Hounoki, Hiroyuki

AU - Kakiuchi, Toshiko

AU - Shinoda, Koichiro

AU - Tobe, Kazuyuki

PY - 2021/8/20

Y1 - 2021/8/20

N2 - A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases.

AB - A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases.

U2 - 10.1155/2021/4416072

DO - 10.1155/2021/4416072

M3 - 学術論文

C2 - 34545315

SN - 2090-6889

VL - 2021

SP - 4416072

JO - Case reports in rheumatology

JF - Case reports in rheumatology

ER -

A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review

Abstract

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