A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland

Tatsuya Yunoki; Jun Murakami; Yukihiro Imagawa; Takahiko Nakajima; Atsushi Hayashi

doi:10.2147/IMCRJ.S123128

A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland

Tatsuya Yunoki^*, Jun Murakami, Yukihiro Imagawa, Takahiko Nakajima, Atsushi Hayashi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

A 60-year-old woman presented with acute eyelid swelling and a subcutaneous hemorrhage in the right eye. Magnetic resonance imaging showed a spherical tumor of the lacrimal gland. The tumor was removed by the Kroenlein method. We diagnosed as a B-cell lymphoma that is unclassifiable, and intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL) based on its immunohistopathological examination and c-MYC/IgH rearrangement. We administered six cycles of dose-adjusted- EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin hydrochloride, and rituximab) therapy, and remission of the lymphoma was obtained. This is the first case of an intermediate DLBCL/BL of a lacrimal gland.

Original language	English
Pages (from-to)	31-33
Number of pages	3
Journal	International Medical Case Reports Journal
Volume	10
DOIs	https://doi.org/10.2147/IMCRJ.S123128
State	Published - 2017/02/01

Keywords

Burkitt lymphoma
C-MYC gene
Diffuse large B-cell lymphoma
Fluorescence in situ hybridization

ASJC Scopus subject areas

General Medicine

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10.2147/IMCRJ.S123128

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title = "A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland",

abstract = "A 60-year-old woman presented with acute eyelid swelling and a subcutaneous hemorrhage in the right eye. Magnetic resonance imaging showed a spherical tumor of the lacrimal gland. The tumor was removed by the Kroenlein method. We diagnosed as a B-cell lymphoma that is unclassifiable, and intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL) based on its immunohistopathological examination and c-MYC/IgH rearrangement. We administered six cycles of dose-adjusted- EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin hydrochloride, and rituximab) therapy, and remission of the lymphoma was obtained. This is the first case of an intermediate DLBCL/BL of a lacrimal gland.",

keywords = "Burkitt lymphoma, C-MYC gene, Diffuse large B-cell lymphoma, Fluorescence in situ hybridization",

author = "Tatsuya Yunoki and Jun Murakami and Yukihiro Imagawa and Takahiko Nakajima and Atsushi Hayashi",

note = "Publisher Copyright: {\textcopyright} 2017 Yunoki et al.",

year = "2017",

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doi = "10.2147/IMCRJ.S123128",

language = "英語",

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T1 - A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland

AU - Yunoki, Tatsuya

AU - Murakami, Jun

AU - Imagawa, Yukihiro

AU - Nakajima, Takahiko

AU - Hayashi, Atsushi

PY - 2017/2/1

Y1 - 2017/2/1

N2 - A 60-year-old woman presented with acute eyelid swelling and a subcutaneous hemorrhage in the right eye. Magnetic resonance imaging showed a spherical tumor of the lacrimal gland. The tumor was removed by the Kroenlein method. We diagnosed as a B-cell lymphoma that is unclassifiable, and intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL) based on its immunohistopathological examination and c-MYC/IgH rearrangement. We administered six cycles of dose-adjusted- EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin hydrochloride, and rituximab) therapy, and remission of the lymphoma was obtained. This is the first case of an intermediate DLBCL/BL of a lacrimal gland.

AB - A 60-year-old woman presented with acute eyelid swelling and a subcutaneous hemorrhage in the right eye. Magnetic resonance imaging showed a spherical tumor of the lacrimal gland. The tumor was removed by the Kroenlein method. We diagnosed as a B-cell lymphoma that is unclassifiable, and intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma (BL) (intermediate DLBCL/BL) based on its immunohistopathological examination and c-MYC/IgH rearrangement. We administered six cycles of dose-adjusted- EPOCH-R (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin hydrochloride, and rituximab) therapy, and remission of the lymphoma was obtained. This is the first case of an intermediate DLBCL/BL of a lacrimal gland.

KW - Burkitt lymphoma

KW - C-MYC gene

KW - Diffuse large B-cell lymphoma

KW - Fluorescence in situ hybridization

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DO - 10.2147/IMCRJ.S123128

M3 - 学術論文

AN - SCOPUS:85011949550

SN - 1179-142X

VL - 10

SP - 31

EP - 33

JO - International Medical Case Reports Journal

JF - International Medical Case Reports Journal

ER -

A B-cell lymphoma case that is unclassifiable, and intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma of lacrimal gland

Abstract

Keywords

ASJC Scopus subject areas

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