2(3H)- and 2 (5H)-furanones. III. An efficient synthesis and the Eschenmoser-Mannich reaction of N-substituted 4-amino-2(5(H)-furanones

Takefumi Momose; Naoki Toyooka; Takafumi Nishi; Yumi Takeuchi

doi:10.3987/COM-88-4594

2(3H)- and 2 (5H)-furanones. III. An efficient synthesis and the Eschenmoser-Mannich reaction of N-substituted 4-amino-2(5(H)-furanones

Takefumi Momose^*, Naoki Toyooka, Takafumi Nishi, Yumi Takeuchi

^*Corresponding author for this work

Life Sciences and Bioengineering

Research output: Contribution to journal › Article › peer-review

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Abstract

A series of N-substituted 4-amino-2(5H)-furanones (II) was derived from β-tetronic acid (I) by direct action of several aliphatic and aromatic amines. The Eschenmoser-Mannich reaction of II readily gave the corresponding Mannich bases (VI) quantitatively.

Original language	English
Pages (from-to)	1907-1923
Number of pages	17
Journal	Heterocycles
Volume	27
Issue number	8
DOIs	https://doi.org/10.3987/COM-88-4594
State	Published - 1988/08/01

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "2(3H)- and 2 (5H)-furanones. III. An efficient synthesis and the Eschenmoser-Mannich reaction of N-substituted 4-amino-2(5(H)-furanones",

abstract = "A series of N-substituted 4-amino-2(5H)-furanones (II) was derived from β-tetronic acid (I) by direct action of several aliphatic and aromatic amines. The Eschenmoser-Mannich reaction of II readily gave the corresponding Mannich bases (VI) quantitatively.",

author = "Takefumi Momose and Naoki Toyooka and Takafumi Nishi and Yumi Takeuchi",

year = "1988",

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AU - Momose, Takefumi

AU - Toyooka, Naoki

AU - Nishi, Takafumi

AU - Takeuchi, Yumi

PY - 1988/8/1

Y1 - 1988/8/1

N2 - A series of N-substituted 4-amino-2(5H)-furanones (II) was derived from β-tetronic acid (I) by direct action of several aliphatic and aromatic amines. The Eschenmoser-Mannich reaction of II readily gave the corresponding Mannich bases (VI) quantitatively.

AB - A series of N-substituted 4-amino-2(5H)-furanones (II) was derived from β-tetronic acid (I) by direct action of several aliphatic and aromatic amines. The Eschenmoser-Mannich reaction of II readily gave the corresponding Mannich bases (VI) quantitatively.

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U2 - 10.3987/COM-88-4594

DO - 10.3987/COM-88-4594

M3 - 学術論文

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SN - 0385-5414

VL - 27

SP - 1907

EP - 1923

JO - Heterocycles

JF - Heterocycles

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ER -

2(3H)- and 2 (5H)-furanones. III. An efficient synthesis and the Eschenmoser-Mannich reaction of N-substituted 4-amino-2(5(H)-furanones

Abstract

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