Project Details
Description
We investigate apolipoprotein A-I-lipid membrane interaction to elucidate mechanism of the formation of HDLs, which act as anti-atherogenic. We found discoidal lipid-apolipoprotein complexes are spontaneously formed by the change in the lipid compositions and pH at membrane's surface. Structure and lipid dynamics of the discoidal complexes were also evaluated by means of neutron scattering and fluorescence analyses.
| Status | Finished |
|---|---|
| Effective start/end date | 2008/04/01 → 2010/03/31 |
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