Transport mechanisms of cell-penetrating peptides at the blood-retinal barrier to establish strategies of macromolecular drug delivery

Akanuma, Shin-ichi (Principal Investigator)
泉尾, 直孝 (Co-Investigator(Kenkyū-buntansha))
Hosoya, Ken-ichi (Co-Investigator(Kenkyū-buntansha))

Biopharmaceutics

4 Article

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2023

Carrier-Mediated Process of Putrescine Elimination at the Rat Blood?Retinal Barrier
Y, T., Y, K., H, M., K, R., A, T., S, A. & K, H., 2023, In: Int J Mol Sci. 24, 10, p. 9003-9003
Research output: Contribution to journal › Article › peer-review
Characterization of LysoTracker Red uptake by in vitro model cells of the outer blood-retinal barrier: Implication of lysosomal trapping with cytoplasmic vacuolation and cytotoxicity
Tega, Y., Takeuchi, T., Nagano, M., Makino, R., Kubo, Y., Akanuma, S. I. & Hosoya, K. I., 2023/08, In: Drug Metabolism and Pharmacokinetics. 51, 100510.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
2022
Lipopolysaccharide-Induced Functional Alteration of P-glycoprotein in the Ex Vivo Rat Inner Blood–Retinal Barrier
Daikohara, K., Akanuma, S. I., Kubo, Y. & Hosoya, K. I., 2022/12, In: International Journal of Molecular Sciences. 23, 24, 15504.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Newly-established in vitro inner BRB spheroids to elucidate retinal Ang2-linked substance transfer
Yamamoto, Y., Akanuma, S. I., Kon, H., Endo, H., Kubo, Y. & Hosoya, K. I., 2022/11, In: Journal of Controlled Release. 351, p. 8-21 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations