Research output per year
Research output per year
Project Details
Abstract
In 23rdfiscal year, we succeeded in developing the CREB phosphorylation detecting system using anesthesized mouse by adjasting the timing and amount of anesthesia. In this year, we succeeded in observing CREB phosphorylation in non-anesthesized mouse. We confirmed acute adminidtration of Fluoxetine up-regulated the light intensity from mouse brain which indicated the CREB phosphorylation. And we also confirmed the up-regulation of CREB phosphorylation after Fluoxetine treatment by westernblotting.
| Status | Finished |
|---|---|
| Effective start/end date | 2011/01/01 → 2012/12/31 |
Funding
- Japan Society for the Promotion of Science: ¥3,640,000.00
Keywords
- トランスジェニックマウス
- ルシフェラーゼ
- ＣＲＥＢ
- 発光計測
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Measuring CREB activation using bioluminescent probes that detect KID-KIX Interaction in living cells
Ishimoto, T., Mano, H., Ozawa, T. & Mori, H., 2012/05/16, In: Bioconjugate Chemistry. 23, 5, p. 923-932 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Regulation of gene expression in retrovirus vectors by X-ray and proton beam radiation with artificially constructed promoters
Ogawa, R., Morii, A., Watanabe, A., Cui, Z. G., Kagiya, G., Fukuda, S., Kume, K., Hasegawa, T., Hatashita, M., Izumi, H., Ishimoto, T. & Feril, L. B., 2012/05, In: Journal of Gene Medicine. 14, 5, p. 316-327 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice
Izumi, H., Ishimoto, T., Yamamoto, H., Nishijo, H. & Mori, H., 2011/06, In: Brain Structure and Function. 216, 2, p. 91-104 14 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations