抗原特異的T細胞受容体の迅速クローニング及び抗原タンパク質の同定法の開発

Kishi, Hiroyuki (PI)

Faculty of Medicine

14 Presentation
5 Article

19 results

2013
A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days
Kobayashi, E., Mizukoshi, E., Kishi, H., Ozawa, T., Hamana, H., Nagai, T., Nakagawa, H., Jin, A., Kaneko, S. & Muraguchi, A., 2013/11, In: Nature Medicine. 19, 11, p. 1542-1546 5 p.
Research output: Contribution to journal › Article › peer-review
78 Scopus citations
Cis-interaction of TCR and antigenic peptides with MHC class I molecules on a CD8+ T-cell.
H, K., A, J., H, H., K, T., E, K., T, O. & A, M., 2013.
Research output: Contribution to conference › Presentation
Cloning and functional analysis of human telomerase reverse transcriptase (hTERT)-specific TCRs from peptide-vaccinated patients.
E, K., H, N., H, H., H, K., T, O., A, J. & A, M., 2013.
Research output: Contribution to conference › Presentation
Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy.
E, K., E, M., H, K., H, H., T, N., T, O., H, N., A, J., S, K. & A, M., 2013.
Research output: Contribution to conference › Presentation
Comparison of -fetoprotein-specific TCR repertoires from hepatocellular carcinoma patients after peptide vaccine treatment and healthy donors.
H, N., E, K., H, H., T, O., H, K. & A, M., 2013.
Research output: Contribution to conference › Presentation
Construction of T cell antigen-exploring system.
X, P., H, H., H, K., E, K., T, O. & A, M., 2013.
Research output: Contribution to conference › Presentation
Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip.
H, K., A, J., H, H., K, T., S, H., E, K., T, O., T, N. & A, M., 2013.
Research output: Contribution to conference › Presentation
Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip.
H, K., A, J., H, H., K, T., S, H., E, K., T, O., T, N. & A, M., 2013.
Research output: Contribution to conference › Presentation
hTEC4 system that enable us to clone TCR cDNA from antigen specific single T cells with in 4 days.
H, H., E, K., H, K., T, O., H, N., A, J. & A, M., 2013.
Research output: Contribution to conference › Presentation
Polymeric microfluidic devices exhibiting sufficient capture of cancer cell line for isolation of circulating tumor cells
Ohnaga, T., Shimada, Y., Moriyama, M., Kishi, H., Obata, T., Takata, K., Okumura, T., Nagata, T., Muraguchi, A. & Tsukada, K., 2013/08, In: Biomedical Microdevices. 15, 4, p. 611-616 6 p.
Research output: Contribution to journal › Article › peer-review
28 Scopus citations
がん抗原特異的TCR遺伝子の迅速クローニング法
小林栄治, 水腰英四郎, 岸　裕幸, 金子周一 & 村口　篤, 2013.
Research output: Contribution to conference › Presentation
2014
A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells
Kobayashi, E., Kishi, H., Ozawa, T., Hamana, H., Nakagawa, H., Jin, A., Lin, Z. & Muraguchi, A., 2014/10/31, In: Biochemical and Biophysical Research Communications. 453, 4, p. 798-803 6 p.
Research output: Contribution to journal › Article › peer-review
34 Scopus citations
A novel system for cloning human TCRs: Cutting short the way to TCR-based anticancer therapy
Kobayashi, E., Kishi, H. & Muraguchi, A., 2014, In: OncoImmunology. 3, 1, e27258.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Cis-interaction of TCR and antigen/MHC class I complexes on a CD8+ T cell
H, K., H, H., K, T., T, O. & A., M., 2014.
Research output: Contribution to conference › Presentation
Development of simple and efficient method for amplification of TCR α β cDNA from single human T cells.
H, H., H, K., T, O. & A., M., 2014.
Research output: Contribution to conference › Presentation
Identification of T cell antigen by an artificial reporter-cell system.
X, P., E, K., H, K., H, H., T, O. & A., M., 2014.
Research output: Contribution to conference › Presentation
Retroviral vectors for homologous recombination provide efficient cloning and expression in mammalian cells
Kobayashi, E., Kishi, H., Ozawa, T., Horii, M., Hamana, H., Nagai, T. & Muraguchi, A., 2014/02/14, In: Biochemical and Biophysical Research Communications. 444, 3, p. 319-324 6 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Single cell analysis of TCR repertoire of CD4+ T cells in PBMC of a melanoma patient and healthy volunteers.
H, K., E, K., D, S., H, N., S, S. & A., M., 2014.
Research output: Contribution to conference › Presentation
メラノーマ患者および健常人の末梢血CD4+ T細胞の単一細胞レベルでのレパートリー解析
岸　裕幸, 浜名　洋, 小林栄治, 杉山大介, 西川博嘉, 鬼塚志乃, 坂口志文 & 村口　篤, 2014.
Research output: Contribution to conference › Presentation