十全大補湯の抗腫瘍効果の分子病理学的解明:新規抗癌剤開発の糸口

Research output

Research output per year 2008 2008 2009 2010 2011 2011

• 27 Article
• 5 Presentation

Research output per year

Research output per year

Search results

• 2011

  Cytoplasmic expression of p331NGlb is correlated with tumorigenesis and progression of head and neck squamous cell carcinoma

  XH, L., A, N., T, N., H, T., Y, Z., XH, Y., S, M., K, K. & Y., T., 2011, In: Histol Histopathol. 25. 26, p. 597-607

  Research output: Contribution to journal › Article › peer-review

• Downregulation and translocation of nuclear ING4 is correlated with tumorigenesis and progression of head and neck squamous cell carcinoma

  Li, X. H., Kikuchi, K., Zheng, Y., Noguchi, A., Takahashi, H., Nishida, T., Masuda, S., Yang, X. H. & Takano, Y., 2011/03, In: Oral Oncology. 47, 3, p. 217-223 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Carcinogenesis 100%
  • Downregulation 100%
  • P21 100%
  • Head-and-neck Squamous Cell Carcinoma (HNSCC) 100%
  • Tumorigenesis 100%
  24 Scopus citations

• Expression Profile of the REG Gene Family in Colorectal Carcinoma

  HC, Z., A, S., H, O., S, T., H, T., S, M. & Y., T., 2011, In: Journal of Histochemistry and Cytochemistry. 59, p. 106-115

  Research output: Contribution to journal › Article › peer-review

• Invasion of breast cancer cells into collagen matrix requires TGF-a and Cdc42 signaling

  K, K., X, L., Y, Z. & Y., T., 2011, In: FEBS Lett. 584. 585, p. 286-290

  Research output: Contribution to journal › Article › peer-review

• Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis

  H, T., JP, W., HC, Z., S, M. & Y., T., 2011, In: Histology and Histopathology. 26, p. 663-71

  Research output: Contribution to journal › Article › peer-review

• The nuclear to cytoplasmic shift of ING5 protein during colorectal carcinogenesis with their distinct links to pathological behaviors of carcinomas

  HC, Z., P, X., XY, X., H, T., YF, G. & Y., T., 2011, In: Hum Pathol. 41. 42, p. 424-433

  Research output: Contribution to journal › Article › peer-review

• Up-regulated EMMPRIN/CD147 protein expression might play a role in colorectal carcinogenesis and its subsequent progression

  HC, Z., W, W., XY, X., P, X., M, Y., T, S. & Y., T., 2011, In: Journal of Cancer Research and Clinical Oncology. 137, p. 585-596

  Research output: Contribution to journal › Article › peer-review
• 2010

  Identification of candidate genes involved in endogenous protection mechanisms against acute pancreatitis in mice

  Nakada, S., Tsuneyama, K., Kato, I., Tabuchi, Y., Takasaki, I., Furusawa, Y., Kawaguchi, H., Fujimoto, M., Goto, H., Hikiami, H., Kondo, T., Takano, Y. & Shimada, Y., 2010/01/15, In: Biochemical and Biophysical Research Communications. 391, 3, p. 1342-1347 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Pancreatitis 100%
  • Caerulein 100%
  • Protection Mechanism 100%
  • Endogenous Protection 100%
  • Claudin 100%
  18 Scopus citations

• Involvement of inactive GSK3beta overexpression in tumorigenesis and progression of gastric carcinomas

  HC, Z., XY, X., P, X., M, Y., H, T. & Y., T., 2010, In: Hum Pathol. 41. 41, p. 1255-1264

  Research output: Contribution to journal › Article › peer-review

• Nuclear or cytoplasmic localization of Bag-1 distinctly correlates with pathologic behavior and outcome of gastric carcinomas.

  HC, Z., XY, X., YN, X., ZL, W., Takahashi, H, S, M. & Y., T., 2010, In: Human Pathology. 41, p. 724-736

  Research output: Contribution to journal › Article › peer-review

• REG IV overexpression in an early stage of colorectal carcinogenesis : An immunohistochemical study.

  XH, L., Y, Z., HC, Z., H, T., XH, Y., S, M. & Y., T., 2010, In: Histol Histopathol. 25. p. 473-484

  Research output: Contribution to journal › Article › peer-review

• The pathobiological behaviors and prognosis associated with Japanese gastric adenocarcinomas of pure WHO histological subtypes.

  HC, Z., YS, Z., P, X., XY, X., YN, X., H, T., YF, G. & Y., T., 2010, In: Histology and Histopathology. 25, p. 445-452

  Research output: Contribution to journal › Article › peer-review

• The role of Reg IV gene and its encoding product in gastric carcino genesis.

  HC, Z., Xu, XY, M, Y., H, T., S, M. & Y., T., 2010, In: Hum Pathol. 41. p. 59-69

  Research output: Contribution to journal › Article › peer-review
• 2009

  Increased death receptor pathway of apoptotic signaling in septic mouse aorta : effect of systemic delivery of FADD siRNA

  N, M., H, T., S, Y., K, T., Y, T. & Y., H., 2009, In: Am J Physiol Heart Circ Physiol. 298.

  Research output: Contribution to journal › Article › peer-review

• Interstitial cells of Cajal do not harbor c-kit or PDGFRA gene mutations in patients with sporadic gastrointestinal stromal tumors

  Nakajima, T., Miwa, S., Ando, T., Fujinami, H., Kajiura, S., Hosokawa, A., Takano, Y. & Sugiyama, T., 2009, In: Journal of Gastroenterology. 44, 5, p. 426-431 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene mutation 100%
  • Gastrointestinal Stromal Tumor 100%
  • KIT Gene 100%
  • Interstitial Cells of Cajal 100%
  • PDGFRA mutation 100%
  8 Scopus citations

• Mapping the research history, situation and fronts about John Cunning ham virus- a bibliometric analysis.

  Zheng, HO, Takano., Y. & al, E., 2009, In: BMC Infectious Disease 9. p. 28-39

  Research output: Contribution to journal › Article › peer-review

• PTEN expression and mutation in colorectal carcinomas.

  XH, L., HC, Z., H, T., S, M., XH, Y. & Y., T., 2009, In: Oncol Rep. 22. p. 757-764

  Research output: Contribution to journal › Article › peer-review

• Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption

  Koizumi, K., Saitoh, Y., Minami, T., Takeno, N., Tsuneyama, K., Miyahara, T., Nakayama, T., Sakurai, H., Takano, Y., Nishimura, M., Imai, T., Yoshie, O. & Saiki, I., 2009/12/15, In: Journal of Immunology. 183, 12, p. 7825-7831 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteoclastogenesis 100%
  • Osteolysis 100%
  • Fractalkine 100%
  • CX3CL1 100%
  • CX3CR1 100%
  122 Scopus citations

• Silencing of Fas-associated death domain protects mice from septic lung inflammation and apoptosis

  Matsuda, N., Yamamoto, S., Takano, K. I., Kageyama, S. I., Kurobe, Y., Yoshihara, Y., Takano, Y. & Hattori, Y., 2009/05/01, In: American Journal of Respiratory and Critical Care Medicine. 179, 9, p. 806-815 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Apoptosis 100%
  • Small Interfering RNA (siRNA) 100%
  • Lung Inflammation 100%
  • Fas-associated Death Domain 100%
  • Programmed Cell Death 100%
  72 Scopus citations

• SV40 T antigen disrupted the cell metabolism and the balance between proliferation and apoptosis in lens tumors of transgenic mice

  Zheng, H. C., Nakamura, T., Zheng, Y., Nakanishi, Y., Tabuchi, Y., Uchiyama, A., Takahashi, H. & Takano, Y., 2009, In: Journal of Cancer Research and Clinical Oncology. 135, 11, p. 1521-1532 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Tumor 100%
  • Apoptosis 100%
  • Transgenic Mice 100%
  • Virus 100%
  • Cell Metabolism 100%
  18 Scopus citations
• 2008

  Aberrant Pim-3 expression is involved in gastric adenoma-adenocarcinoma sequence and cancer progression

  HC, Z., Y., T. & al, E., 2008, In: J Cancer Res Clin Oncol. 134. p. 481-488

  Research output: Contribution to journal › Article › peer-review

• Arp2/3 overexpression contributed to pathogenesis, growth and invasion of gastric carcinoma

  HC, Z., Y., T. & al, E., 2008, In: Anticancer Research. p. 2225-2232

  Research output: Contribution to journal › Article › peer-review

• Cytoplasmic and nuclear maspin expression in lung carcinomas : an immunohistochemical study using tissue microarrays.

  HC, Z., Y., T. & al, E., 2008, In: Applied Immunohistochemistry and Molecular Morphology. p. 459-465

  Research output: Contribution to journal › Article › peer-review

• High JC virus load in tongue carcinomas may be a risk factor for tongue tumorigenesis.

  T, K., H, Z., Y., T. & al, E., 2008, In: Virchows Archiv 452. p. 405-410

  Research output: Contribution to journal › Article › peer-review

• Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas.

  HC, Z., Y., T. & al, E., 2008, In: Human Pathology 39. p. 1042-1049

  Research output: Contribution to journal › Article › peer-review

• Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: An oligonucleotide microarray study

  Abdel-Aziz, H. O., Murai, Y., Takasaki, I., Tabuchi, Y., Zheng, H. C., Nomoto, K., Takahashi, H., Tsuneyama, K., Kato, I., Hsu, D. K., Liu, F. T., Hiraga, K. & Takano, Y., 2008/07, In: Journal of Cancer Research and Clinical Oncology. 134, 7, p. 777-788 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Decreased Susceptibility 100%
  • Galectin-3 (Gal-3) 100%
  • Microarray Profiling 100%
  • Oligonucleotide Array 100%
  • Targeted Disruption 100%
  33 Scopus citations

• The clinicopathological and prognostic significance of MUC-1 expression in Japanese gastric carcinomas : an immunohistochemical study of tissue microarrays.

  XH, L., HC, Z., Y., T. & al, E., 2008, In: Anticancer Research. p. 1061-67

  Research output: Contribution to journal › Article › peer-review