Research output per year
Research output per year
Project Details
Abstract
We examined expression of several chemokine receptors in human solid cancer such as gastric, colorectal, liver, ovarian cancer cell lines. These cell lines selectively expressed CXCR4 at high levels. These cells showed significant chemotactic response to CXCL12 in Boyden chemotaxis chamber. However, this response could not be observed in Real-time migration activity monitoring device. On the other hand, flexibility of the kineticism of these cells increased.
| Status | Finished |
|---|---|
| Effective start/end date | 2010/01/01 → 2012/12/31 |
Funding
- Japan Society for the Promotion of Science: ¥4,420,000.00
Keywords
- ドラッグデリバリー
- ケモカイン
- がん細胞
- 遊走
- 方向性
- がん
Research output
- 5 Article
-
Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model
Kee, J. Y., Ito, A., Hojo, S., Hashimoto, I., Igarashi, Y., Tsukada, K., Irimura, T., Shibahara, N., Nakayama, T., Yoshie, O., Sakurai, H., Saiki, I. & Koizumi, K., 2013/03, In: Oncology Reports. 29, 3, p. 975-982 8 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Periostin Directly and Indirectly Promotes Tumor Lymphangiogenesis of Head and Neck Cancer
Kudo, Y., Iizuka, S., Yoshida, M., Nguyen, P. T., Siriwardena, S. B. S. M., Tsunematsu, T., Ohbayashi, M., Ando, T., Hatakeyama, D., Shibata, T., Koizumi, K., Maeda, M., Ishimaru, N., Ogawa, I. & Takata, T., 2012/08/30, In: PLoS ONE. 7, 8, e44488.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Therapeutics target of CXCR4 and its downstream in peritoneal carcinomatosis of gastric cancer
Koizumi, K., Kato, S., Sakurai, H., Hashimoto, I., Yasumoto, K. & Saiki, I., 2012/01/01, In: Frontiers in Bioscience - Scholar. 4 S, 1, p. 269-276 8 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations