Yuma Tega

2025

In vitro characterization of taurine transport using the human brain microvascular endothelial cell line as a human blood-brain barrier model

Tega, Y., Kawauchi, Y., Akanuma, S. I., Inagaki, M., Tachikawa, M. & Hosoya, K. I., 2025/04, In: Drug Metabolism and Pharmacokinetics. 61, 101040.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Neuroprotective effects of compounds interacting with carrier-mediated amantadine transport across the blood–retinal barrier in rats

Shinozaki, Y., Akanuma, S. I., Tega, Y. & Hosoya, K. I., 2025/04, In: Journal of Pharmacological Sciences. 157, 4, p. 212-218 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Blood-to-Testis Transport of Ribavirin Involves Carrier-Mediated Processes at the Blood–Testis Barrier

Ito, T., Kubo, Y., Tega, Y., Akanuma, S. I. & Hosoya, K. I., 2024, (Accepted/In press) In: Journal of Pharmaceutical Sciences.

Research output: Contribution to journal › Article › peer-review

Open Access

Molecular Mechanism of SLC6A8 Dysfunction with c.1699T>C (p.S567P) Mutation in Cerebral Creatine Deficiency Syndromes

Jomura, R., Sawada, M., Tega, Y., Akanuma, S. I., Tachikawa, M. & Hosoya, K. I., 2024/01, In: Biological and Pharmaceutical Bulletin. 47, 1, p. 187-191 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Upregulation of P-Glycoprotein and Breast Cancer Resistance Protein Activity in Newly Developed in Vitro Rat Blood–Brain Barrier Spheroids Using Advanced Glycation End-Products

Endo, H., Ogasawara, M., Tega, Y., Kubo, Y., Hosoya, K. I. & Akanuma, S. I., 2024/11, In: Biological and Pharmaceutical Bulletin. 47, 11, p. 1893-1903 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Characterization of LysoTracker Red uptake by in vitro model cells of the outer blood-retinal barrier: Implication of lysosomal trapping with cytoplasmic vacuolation and cytotoxicity

Tega, Y., Takeuchi, T., Nagano, M., Makino, R., Kubo, Y., Akanuma, S. I. & Hosoya, K. I., 2023/08, In: Drug Metabolism and Pharmacokinetics. 51, 100510.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2022

Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells

Kurosawa, T., Sako, D., Tega, Y., Debori, Y., Tomihara, Y., Aoyama, K., Kubo, Y., Amano, N. & Deguchi, Y., 2022/07, In: Pharmaceutical Research. 39, 7, p. 1535-1547 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier

Kurosawa, T., Tega, Y., Uchida, Y., Higuchi, K., Tabata, H., Sumiyoshi, T., Kubo, Y., Terasaki, T. & Deguchi, Y., 2022/08, In: Pharmaceutics. 14, 8, 1683.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2018

Expression and Functional Characterization of Drug Transporters in Brain Microvascular Endothelial Cells Derived from Human Induced Pluripotent Stem Cells

Kurosawa, T., Tega, Y., Higuchi, K., Yamaguchi, T., Nakakura, T., Mochizuki, T., Kusuhara, H., Kawabata, K. & Deguchi, Y., 2018/12/03, In: Molecular Pharmaceutics. 15, 12, p. 5546-5555 10 p.

Research output: Contribution to journal › Article › peer-review