Tsutomu Wada

Activities

Activities per year 2011 2011 2012 2013 2014 2015 2015

• 115 Oral presentation

Activities per year

Search results

• 抗アルドステロン薬による非アルコール性脂肪性肝炎（NASH）とメタボリックシンドローム病態の新規モデルマウスを用いた改善メカニズムの検討．

  Wada, T. (Speaker)

  2013/11/17

  Activity: Talk or presentation › Oral presentation

• Impact of hypothalamic orexin on hepatic insulin resistance induced by chronic social defeat stress in mice.

  Wada, T. (Speaker)

  2013/10/11 → 2013/10/13

  Activity: Talk or presentation › Oral presentation

• AngiotensinⅡ曝露した培養血管内皮細胞でのインスリン抵抗性に対するcoenzyme Q10の効果．

  Wada, T. (Speaker)

  2013/10/06

  Activity: Talk or presentation › Oral presentation

• Hypothalamic orexin generates the circadian metabolic rhythm for maintaining glucose homeostasis in mice.

  Wada, T. (Speaker)

  2013/09/10 → 2013/09/13

  Activity: Talk or presentation › Oral presentation

• Hypothalamic orexin system protects against hepatic insulin resistance induced by chronic social defeat stress in mice.

  Wada, T. (Speaker)

  2013/09/10 → 2013/09/13

  Activity: Talk or presentation › Oral presentation

• Cilostazol improves systemic insulin resistance in diabetic db/db mice by suppressing proinflammatory cytokine production in macrophage and ameliorating insulin signaling in adipocyte.

  Wada, T. (Speaker)

  2013/06/09 → 2013/06/11

  Activity: Talk or presentation › Oral presentation

• 糖代謝に対するPDGFシグナルの関与の解析．

  Wada, T. (Speaker)

  2013/05/16 → 2013/05/18

  Activity: Talk or presentation › Oral presentation

• 5’-リピッドホスファターゼSHIP2阻害薬の開発とインスリン抵抗性改善効果の検討．

  Wada, T. (Speaker)

  2013/05/16 → 2013/05/18

  Activity: Talk or presentation › Oral presentation

• エストロゲン中枢選択的投与の肥満・耐糖能・うつ改善効果に関する検討．

  Wada, T. (Speaker)

  2013/05/16 → 2013/05/18

  Activity: Talk or presentation › Oral presentation

• 視床下部オレキシンの日内リズム制御による２型糖尿病マウスの肝糖代謝の改善効果．

  Wada, T. (Speaker)

  2013/05/16 → 2013/05/18

  Activity: Talk or presentation › Oral presentation

• 慢性的なうつに伴う糖代謝異常に対する視床下部オレキシン系の役割の解析．

  Wada, T. (Speaker)

  2013/05/16 → 2013/05/18

  Activity: Talk or presentation › Oral presentation

• 閉経肥満モデルマウスにおけるエストロゲン末梢または中枢投与のうつ・不安状態に対する改善効果

  Wada, T. (Speaker)

  2013/05/10 → 2013/05/12

  Activity: Talk or presentation › Oral presentation

• 糖尿病に伴う脳機能障害におけるインスリン作用の役割

  Wada, T. (Speaker)

  2013/03/21 → 2013/03/23

  Activity: Talk or presentation › Oral presentation

• 視床下部オレキシンの糖代謝リズム制御による2型糖尿病マウスの高血糖改善効果

  Wada, T. (Speaker)

  2012/12/08

  Activity: Talk or presentation › Oral presentation

• 脳インスリン抵抗性に伴う脳高次機能障害に対するリピッドホスファターゼSHIP2阻害剤の改善効果の解析

  Wada, T. (Speaker)

  2012/11/18

  Activity: Talk or presentation › Oral presentation

• 5’-リピッドホスファターゼSHIP2が摂食行動に与える影響の解析と, SHIP2を標的とした新規耐糖能改善薬の開発

  Wada, T. (Speaker)

  2012/11/18

  Activity: Talk or presentation › Oral presentation

• 閉経肥満モデルマウスにおけるエストロゲンの中枢及び末梢投与が不安とうつに与える影響の検討

  Wada, T. (Speaker)

  2012/11/10

  Activity: Talk or presentation › Oral presentation

• Hypothalamic orexin system regulates daily rhythm of glucose metabolism in the liver of mice.

  Wada, T. (Speaker)

  2012/10/22 → 2012/10/27

  Activity: Talk or presentation › Oral presentation

• Hypothalamic orexin controls the circadian rhythm in glucose metabolism in the liver of mice.

  Wada, T. (Speaker)

  2012/10/19 → 2012/10/21

  Activity: Talk or presentation › Oral presentation

• Characterization of central and peripheral impact of estrogen on the impaired glucose metabolism in postmenopausal obese mice model.

  Wada, T. (Speaker)

  2012/10/19 → 2012/10/21

  Activity: Talk or presentation › Oral presentation

• エストロゲンの末梢または中枢投与が閉経肥満モデルマウスのうつ症状改善に与える影響.

  Wada, T. (Speaker)

  2012/09/08 → 2012/09/09

  Activity: Talk or presentation › Oral presentation

• Central and peripheral estrogen differentially ameliorates impaired glucose metabolism in postmenopausal obese mice model.

  Wada, T. (Speaker)

  2012/06/08 → 2012/06/12

  Activity: Talk or presentation › Oral presentation

• Cilostazol ameliorates systemic insulin resistance by affecting macrophage and adipocyte functions.

  Wada, T. (Speaker)

  2012/06/08 → 2012/06/12

  Activity: Talk or presentation › Oral presentation

• Hypothalamic orexin deficiency causes age related insulin resistance via enhancement of ER stress in the liver of mice.

  Wada, T. (Speaker)

  2012/06/08 → 2012/06/12

  Activity: Talk or presentation › Oral presentation

• 糖尿病病態におけるリピッドホスファターゼSHIP2の増加が脳高次機能に関わるBDNF発現に与える影響

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• うつによるインスリン抵抗性に対する防御機構としての視床下部オレキシンの役割

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• 視床下部オレキシンの欠損によるマウス肝臓の小胞体ストレス応答機構の障害を介した糖産生調節の異常

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• 新規骨格を有する5’-リピッドホスファターゼSHIP2阻害薬の開発とインスリン抵抗性改善効果の検討

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• シロスタゾールによるインスリン抵抗性改善機序の検討

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• 糖尿病モデルマウスの脳高次機能障害に対するCilostazolの改善効果の検討

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• マウスでの持続型インスリンアナログが脳高次機能に及ぼす影響

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• エストロゲンの糖脂質代謝改善作用における中枢及び末梢作用の機能的差異の検討

  Wada, T. (Speaker)

  2012/05/17 → 2012/05/19

  Activity: Talk or presentation › Oral presentation

• 電解質コルチコイド受容体阻害によるインスリン抵抗性病態の改善効果の検討

  Wada, T. (Speaker)

  2012/04/19 → 2012/04/21

  Activity: Talk or presentation › Oral presentation

• エストロゲンの末梢または中枢投与による, 卵巣摘出後高脂肪食負荷マウスの糖脂質代謝とうつ症状に対する改善効果とメカニズムの解析

  Wada, T. (Speaker)

  2012/04/13 → 2012/04/15

  Activity: Talk or presentation › Oral presentation

• ニコチンによる視床下部オレキシン神経を介するマウス肝糖新生の修飾作用

  Wada, T. (Speaker)

  2012/03/14 → 2012/03/16

  Activity: Talk or presentation › Oral presentation

• オレキシン欠損マウスの肝臓における小胞体ストレス応答機構の破綻による糖代謝調節の異常

  Wada, T. (Speaker)

  2012/03/14

  Activity: Talk or presentation › Oral presentation

• Deficiency of hypothalamic orexin causes insulin resistance via enhancement of ER stress in the liver of mice

  Wada, T. (Speaker)

  2012/01/29 → 2012/02/03

  Activity: Talk or presentation › Oral presentation

• Estrogen ameliorates glucose homeostasis by coordinating central and peripheral hormonal actions in a postmenopausal obese model of mice

  Wada, T. (Speaker)

  2012/01/29 → 2012/02/03

  Activity: Talk or presentation › Oral presentation

• インスリンおよび持効型インスリンアナログのマウス脳機能に対する作用特性の検討

  Wada, T. (Speaker)

  2011/11/27

  Activity: Talk or presentation › Oral presentation

• 視床下部オレキシンによる自律神経系を介する糖代謝恒常性の維持機構の解明

  Wada, T. (Speaker)

  2011/11/26

  Activity: Talk or presentation › Oral presentation

• Blockade of mineralocorticoid receptor ameliorates glucose metabolism and steatohepatitis in a novel mice model of non-alcoholic steatohepatitis.

  Wada, T. (Speaker)

  2011/11/10 → 2011/11/12

  Activity: Talk or presentation › Oral presentation

• エストロゲンの中枢性および末梢性代謝調節作用の検討

  Wada, T. (Speaker)

  2011/11/05

  Activity: Talk or presentation › Oral presentation

• エストロゲンの中枢及び末梢投与が全身のエネルギーバランス, 体脂肪分布と糖・脂質代謝に与える影響

  Wada, T. (Speaker)

  2011/08/29 → 2011/08/31

  Activity: Talk or presentation › Oral presentation

• Blockade of mineralocorticoid receptor improves insulin resistance and steatohepatitis in a novel mouse model of non-alchoholic steatohepatitis (NASH) utilizing liver-specific SREBP1c transgenic mice.

  Wada, T. (Speaker)

  2011/06/24 → 2011/06/28

  Activity: Talk or presentation › Oral presentation

• Role of hypothalamic orexin in the regulation of hepatic insulin sensitivity in mice.

  Wada, T. (Speaker)

  2011/06/24 → 2011/06/28

  Activity: Talk or presentation › Oral presentation

• Overexpression of SHIP2 causes insulin but not leptin resistance in the hypothalamus and dysregulation of energy homeostasis in mice.

  Wada, T. (Speaker)

  2011/06/24 → 2011/06/28

  Activity: Talk or presentation › Oral presentation

• Brain signaling of long-acting insulin analogues glargine and detemir for the regulation of glucose metabolism and learning/memory in mice.

  Wada, T. (Speaker)

  2011/06/24 → 2011/06/28

  Activity: Talk or presentation › Oral presentation

• リピッドホスファターゼSHIP2が中枢性エネルギー代謝に与える影響

  Wada, T. (Speaker)

  2011/06/17 → 2011/06/18

  Activity: Talk or presentation › Oral presentation

• 特異的SREBP1c過剰発現と脂肪・果糖負荷による脂肪性肝炎：アルドステロン阻害薬の効果と創薬

  Wada, T. (Speaker)

  2011/06/17 → 2011/06/18

  Activity: Talk or presentation › Oral presentation

• エストロゲンの中枢及び末梢投与が全身のエネルギーバランス、体脂肪分布と糖・脂質代謝に与える影響

  Wada, T. (Speaker)

  2011/05/19 → 2011/05/21

  Activity: Talk or presentation › Oral presentation