Research output per year
Research output per year
- 1 - 50 out of 51 results
Search results
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2024
Modeling Developmental Changes in Caffeine Clearance Considering Differences between Pre- and Postnatal Period
Ide, H., Kawasaki, Y., Tamura, K., Yoshida, T., Fujihara, R., Hara, A. & Taguchi, M., 2024/04, In: Biological and Pharmaceutical Bulletin. 47, p. 861 7 p.Research output: Contribution to journal › Article › peer-review
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2021
Pharmacokinetic variability of caffeine in routinely treated preterm infants: Preliminary considerations on developmental changes of systemic clearance
Taguchi, M., Kawasaki, Y., Katsuma, A., Mito, A., Tamura, K., Makimoto, M. & Yoshida, T., 2021/01/01, In: Biological and Pharmaceutical Bulletin. 44, 1, p. 69-74 6 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2020
CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
Takeuchi, M., Kobayashi, T., Biss, T., Kamali, F., Vear, S. I., Ho, R. H., Bajolle, F., Loriot, M. A., Shaw, K., Carleton, B. C., Hamberg, A. K., Wadelius, M., Hirono, K., Taguchi, M., Wakamiya, T., Yanagimachi, M., Hirai, K., Itoh, K., Brandão, L. R. & Ito, S., 2020/04/01, In: Pharmacogenomics Journal. 20, 2, p. 306-319 14 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
The pharmacokinetics of sildenafil may be affected by intestinal absorption rate in children admitted to the intensive care unit
Oya, Y., Watahiki, D., Matsunaga, M., Hirono, K., Ichida, F., Aoki, M., Yoshimura, N. & Taguchi, M., 2020/12/01, In: Biological and Pharmaceutical Bulletin. 43, 12, p. 1917-1923 7 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2019
Determination of the serum unbound fraction of tadalafil in children with protein-losing enteropathy and its specific binding to human serum proteins in vitro
Shigetomi, N., Kamiya, K., Takamori, T., Yoshimura, N., Ozawa, S., Hirono, K., Ichida, F. & Taguchi, M., 2019, In: Biological and Pharmaceutical Bulletin. 42, 1, p. 110-115 6 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Evaluation of the effects of ontogenetic or maturation functions and chronic heart failure on the model analysis for the dose-response relationship of warfarin in Japanese children
Tamura, R., Watanabe, N., Nakamura, S., Yoshimura, N., Ozawa, S., Hirono, K., Ichida, F. & Taguchi, M., 2019/07, In: European Journal of Clinical Pharmacology. 75, 7, p. 913-920 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2018
The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study
Watanabe, N., Higashi, H., Nakamura, S., Nomura, K., Adachi, Y. & Taguchi, M., 2018/01, In: Biopharmaceutics and Drug Disposition. 39, 1, p. 30-37 8 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2017
In vitro P-Glycoprotein-Mediated transport of tadalafil: A comparison with sildenafil
Higashi, H., Watanabe, N., Tamura, R. & Taguchi, M., 2017, In: Biological and Pharmaceutical Bulletin. 40, 8, p. 1314-1319 6 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2016
A model analysis for dose-response relationship of warfarin in Japanese children: An introduction of the SIZE parameter
Nakamura, S., Watanabe, N., Yoshimura, N., Ozawa, S., Hirono, K., Ichida, F. & Taguchi, M., 2016/06/01, In: Drug Metabolism and Pharmacokinetics. 31, 3, p. 234-241 8 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
In vitro enhancement of carvedilol glucuronidation by amiodarone-mediated altered protein binding in incubation mixture of human liver microsomes with bovine serum albumin
Sekimoto, M., Takamori, T., Nakamura, S. & Taguchi, M., 2016, In: Biological and Pharmaceutical Bulletin. 39, 8, p. 1359-1363 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Contribution of CYP3A isoforms to dealkylation of PDE5 inhibitors: A comparison between sildenafil N-demethylation and tadalafil demethylenation
Takahiro, R., Nakamura, S., Kohno, H., Yoshimura, N., Nakamura, T., Ozawa, S., Hirono, K., Ichida, F. & Taguchi, M., 2015/01/01, In: Biological and Pharmaceutical Bulletin. 38, 1, p. 58-65 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2014
Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats
Yamaura, S., Fukao, M., Ishida, K., Taguchi, M. & Hashimoto, Y., 2014/03, In: European Journal of Drug Metabolism and Pharmacokinetics. 39, 1, p. 53-59 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Pharmacokinetic variability of flecainide in younger Japanese patients and mechanisms for renal excretion and intestinal absorption
Horie, A., Ishida, K., Shibata, K., Taguchi, M., Ozawa, A., Hirono, K., Ichida, F. & Hashimoto, Y., 2014/04, In: Biopharmaceutics and Drug Disposition. 35, 3, p. 145-153 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Plasma concentrations of tadalafil in children with pulmonary arterial hypertension
Kohno, H., Ichida, F., Hirono, K., Ozawa, S., Yoshimura, N., Nakamura, T., Akita, C., Ishida, K. & Taguchi, M., 2014/10/12, In: Therapeutic Drug Monitoring. 36, 5, p. 576-583 8 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Variability of bioavailability and intestinal absorption mechanisms of metoprolol
Fukao, M., Ishida, K., Horie, A., Taguchi, M., Nozawa, T., Inoue, H. & Hashimoto, Y., 2014, In: Drug Metabolism and Pharmacokinetics. 29, 2, p. 162-167 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2013
Effect of salt intake on bioavailability of mizoribine in healthy Japanese males
Ishida, K., Fukao, M., Watanabe, H., Taguchi, M., Miyawaki, T., Matsukura, H., Uemura, O., Zhang, Z., Unadkat, J. D. & Hashimoto, Y., 2013, In: Drug Metabolism and Pharmacokinetics. 28, 1, p. 75-80 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Variability of bioavailability and intestinal absorption characteristics of bisoprolol
Ishida, K., Horie, A., Nishimura, M., Taguchi, M., Fujii, N., Nozawa, T., Inoue, H. & Hashimoto, Y., 2013, In: Drug Metabolism and Pharmacokinetics. 28, 6, p. 491-496 6 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2011
Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells
Horie, A., Sakata, J., Nishimura, M., Ishida, K., Taguchi, M. & Hashimoto, Y., 2011/07, In: Biopharmaceutics and Drug Disposition. 32, 5, p. 253-260 8 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Pharmacokinetics of bosentan in routinely treated Japanese pediatric patients with pulmonary arterial hypertension
Taguchi, M., Ichida, F., Hirono, K., Miyawaki, T., Yoshimura, N., Nakamura, T., Akita, C., Nakayama, T., Saji, T., Kato, Y., Horiuchi, I. & Hashimoto, Y., 2011, In: Drug Metabolism and Pharmacokinetics. 26, 3, p. 280-287 8 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2010
Bosentan induces clinical and hemodynamic improvement in candidates for right-sided heart bypass surgery
Hirono, K., Yoshimura, N., Taguchi, M., Watanabe, K., Nakamura, T., Ichida, F. & Miyawaki, T., 2010, In: Journal of Thoracic and Cardiovascular Surgery. 140, 2, p. 346-351 6 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Inhibitory and stimulative effects of amiodarone on metabolism of carvedilol in human liver microsomes
Horiuchi, I., Kato, Y., Nakamura, A., Ishida, K., Taguchi, M. & Hashimoto, Y., 2010/04/10, In: Biological and Pharmaceutical Bulletin. 33, 4, p. 717-720 4 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells
Masago, M., Takaai, M., Sakata, J., Horie, A., Ito, T., Ishida, K., Taguchi, M. & Hashimoto, Y., 2010, In: Biological and Pharmaceutical Bulletin. 33, 8, p. 1407-1412 6 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2009
A simulation study to evaluate limited sampling strategies to estimate area under the curve of drug concentration versus time following repetitive oral dosing: Limited sampling model versus naive trapezoidal method
Kayano, Y., Horiuchi, I., Mori, Y. I., Ishida, K., Saito, T., Taguchi, M. & Hashimoto, Y., 2009/08, In: Biological and Pharmaceutical Bulletin. 32, 8, p. 1486-1490 5 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Involvement of the CYP1A subfamily in stereoselective metabolism of carvedilol in β-naphthoflavone-treated Caco-2 cells
Ishida, K., Taguchi, M., Akao, T. & Hashimoto, Y., 2009/03, In: Biological and Pharmaceutical Bulletin. 32, 3, p. 513-516 4 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Mechanisms responsible for the altered pharmacokinetics of bosentan: Analysis utilizing rats with bile duct ligation-induced liver dysfunction
Horiuchi, I., Mori, Y. I., Taguchi, M., Ichida, F., Miyawaki, T. & Hashimoto, Y., 2009, In: Biopharmaceutics and Drug Disposition. 30, 6, p. 326-333 8 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells
Ishida, K., Takaai, M., Yotsutani, A., Taguchi, M. & Hashimoto, Y., 2009/04, In: Biological and Pharmaceutical Bulletin. 32, 4, p. 741-745 5 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells
Fukumori, S., Masago, M., Ishida, K., Kayano, Y., Taguchi, M. & Hashimoto, Y., 2009, In: Biopharmaceutics and Drug Disposition. 30, 8, p. 448-456 9 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2008
Additional notes on clinical repeated-dose pharmacokinetic trials applying a peak-and-trough sampling design to estimate oral clearance
Takaai, M., Kayano, Y., Shimizu, T., Taguchi, M. & Hashimoto, Y., 2008, In: Drug Metabolism and Pharmacokinetics. 23, 2, p. 128-133 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Contribution of Na+-independent nucleoside transport to ribavirin uptake in the rat intestine and human epithelial LS180 cells
Takaai, M., Morishita, H., Ishida, K., Taguchi, M. & Hashimoto, Y., 2008/12/28, In: European Journal of Pharmacology. 601, 1-3, p. 61-65 5 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 cells
Tahara, K., Kagawa, Y., Takaai, M., Taguchi, M. & Hashimoto, Y., 2008, In: Drug Metabolism and Pharmacokinetics. 23, 5, p. 340-346 7 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Pharmacokinetics of R- and S-carvedilol in routinely treated Japanese patients with heart failure
Horiuchi, I., Nozawa, T., Fujii, N., Inoue, H., Honda, M., Shimizu, T., Taguchi, M. & Hashimoto, Y., 2008/05, In: Biological and Pharmaceutical Bulletin. 31, 5, p. 976-980 5 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Stereoselective oxidation and glucuronidation of carvedilol in human liver and intestinal microsomes
Ishida, K., Taira, S., Morishita, H., Kayano, Y., Taguchi, M. & Hashimoto, Y., 2008/06, In: Biological and Pharmaceutical Bulletin. 31, 6, p. 1297-1300 4 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells
Fukumori, S., Murata, T., Takaai, M., Tahara, K., Taguchi, M. & Hashimoto, Y., 2008, In: Drug Metabolism and Pharmacokinetics. 23, 5, p. 373-378 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2007
Pharmacokinetics and hepatic extraction of metoprolol in rats with glycerol-induced acute renal failure
Tanabe, H., Taira, S., Taguchi, M. & Hashimoto, Y., 2007/03, In: Biological and Pharmaceutical Bulletin. 30, 3, p. 552-555 4 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Population pharmacokinetics and proton pump inhibitory effects of intravenous lansoprazole in healthy Japanese males
Sakurai, Y., Hirayama, M., Hashimoto, M., Tanaka, T., Hasegawa, S., Irie, S., Ashida, K., Kayano, Y., Taguchi, M. & Hashimoto, Y., 2007/12, In: Biological and Pharmaceutical Bulletin. 30, 12, p. 2238-2243 6 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
Fukumori, S., Murata, T., Taguchi, M. & Hashimoto, Y., 2007/10, In: Drug Metabolism and Pharmacokinetics. 22, 5, p. 377-381 5 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Simulation for clinical repeated-dose pharmacokinetic trials applying a peak-and-trough sampling design to estimate oral clearance
Ishida, K., Kayano, Y., Taguchi, M. & Hashimoto, Y., 2007/11, In: Biological and Pharmaceutical Bulletin. 30, 11, p. 2159-2162 4 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Stereoselective metabolism of carvedilol by the β-naphthoflavone- inducible enzyme in human intestinal epithelial Caco-2 cells
Ishida, K., Honda, M., Shimizu, T., Taguchi, M. & Hashimoto, Y., 2007/10, In: Biological and Pharmaceutical Bulletin. 30, 10, p. 1930-1933 4 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
UGT2B7*3 did not affect the pharmacokinetics of R- and S-carvedilol in healthy Japanese.
Honda, M., Toyoda, W., Shimizu, T., Horiuchi, I., Kayano, Y., Taguchi, M., Nozawa, T., Inoue, H. & Hashimoto, Y., 2007/10, In: Drug Metabolism and Pharmacokinetics. 22, 5, p. 382-386 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2006
Endogenous uremic substances are not involved in the reduced hepatic extraction of metoprolol in bilateral ureter-ligated rats.
Taguchi, M., Urai, M., Taira, S., Tanabe, H. & Hashimoto, Y., 2006/04, In: Drug Metabolism and Pharmacokinetics. 21, 2, p. 156-164 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Multiple regression analysis of pharmacogenetic variability of carvedilol disposition in 54 healthy Japanese volunteers
Honda, M., Ogura, Y., Toyoda, W., Taguchi, M., Nozawa, T., Inoue, H. & Hashimoto, Y., 2006/04, In: Biological and Pharmaceutical Bulletin. 29, 4, p. 772-778 7 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias
Taguchi, M., Fujiki, A., Iwamoto, J., Inoue, H., Tahara, K., Saigusa, K., Horiuchi, I., Oshima, Y. & Hashimoto, Y., 2006/03, In: Biological and Pharmaceutical Bulletin. 29, 3, p. 517-521 5 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Pharmacokinetics and pharmacodynamics of bisoprolol in rats with bilateral ureter ligation-induced renal failure.
Tahara, K., Saigusa, K., Kagawa, Y., Taguchi, M. & Hashimoto, Y., 2006/10, In: Drug Metabolism and Pharmacokinetics. 21, 5, p. 389-394 6 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2005
Effect of CYP2D6*10 on the pharmacokinetics of R- and S-carvedilol in healthy Japanese volunteers
Honda, M., Nozawa, T., Igarashi, N., Inoue, H., Arakawa, R., Ogura, Y., Okabe, H., Taguchi, M. & Hashimoto, Y., 2005/08, In: Biological and Pharmaceutical Bulletin. 28, 8, p. 1476-1479 4 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients.
Taguchi, M., Hongou, K., Yagi, S., Miyawaki, T., Takizawa, M., Aiba, T. & Hashimoto, Y., 2005/04, In: Drug Metabolism and Pharmacokinetics. 20, 2, p. 107-112 6 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Influence of CYP2D6 genotype on metoprolol plasma concentration and β-adrenergic inhibition during long-term treatment: A comparison with bisoprolol
Nozawa, T., Taguchi, M., Tahara, K., Hashimoto, Y., Igarashi, N., Nonomura, M., Kato, B. I., Igawa, A. & Inoue, H., 2005/11, In: Journal of Cardiovascular Pharmacology. 46, 5, p. 713-720 8 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
Mechanism responsible for the decreased hepatic NADPH generation rate in rats with bilateral ureter ligation-induced renal failure
Higashi, T., Urai, M., Taguchi, M. & Hashimoto, Y., 2005/09, In: Biological and Pharmaceutical Bulletin. 28, 9, p. 1809-1812 4 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Pharmacokinetic variability of routinely administered bisoprolol in middle-aged and elderly Japanese patients
Taguchi, M., Nozawa, T., Igawa, A., Inoue, H., Takesono, C., Tahara, K. & Hashimoto, Y., 2005/05, In: Biological and Pharmaceutical Bulletin. 28, 5, p. 876-881 6 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
2004
Nonlinear mixed effects model analysis of the pharmacokinetics of metoprolol in routinely treated Japanese patients
Taguchi, M., Nozawa, T., Mizumaki, K., Inoue, H., Tahara, K., Takesono, C. & Hashimoto, Y., 2004/10, In: Biological and Pharmaceutical Bulletin. 27, 10, p. 1642-1648 7 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2003
Effect of CYP2D6*10 on pharmacokinetic variability of routinely administered metoprolol in middle-aged and elderly Japanese patients
Taguchi, M., Nozawa, T., Kameyama, T., Inoue, H., Takesono, C., Mizukami, A. & Hashimoto, Y., 2003/09/01, In: European Journal of Clinical Pharmacology. 59, 5-6, p. 385-388 4 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations