Total Synthesis of Discorhabdin C: A General Aza Spiro Dienone Formation from O-Silylated Phenol Derivatives Using a Hypervalent Iodine Reagent

Yasuyuki Kita; Hirofumi Tohma; Masanao Inagaki; Kenji Hatanaka; Takayuki Yakura

doi:10.1021/ja00032a036

Total Synthesis of Discorhabdin C: A General Aza Spiro Dienone Formation from O-Silylated Phenol Derivatives Using a Hypervalent Iodine Reagent

Yasuyuki Kita, Hirofumi Tohma, Masanao Inagaki, Kenji Hatanaka, Takayuki Yakura^*

^*この論文の責任著者

分子合成化学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

196 被引用数 (Scopus)

抄録

Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the para position in 2,2,2-trifluoroethanol gave azacarbocyclic spiro dienones in good yields. Using this method, the first total synthesis of discorhabdin C, which was isolated from the sponge of Latrunculia du Bocage in New Zealand, was achieved.

本文言語	英語
ページ（範囲）	2175-2180
ページ数	6
ジャーナル	Journal of the American Chemical Society
巻	114
号	6
DOI	https://doi.org/10.1021/ja00032a036
出版ステータス	出版済み - 1992/03/01

ASJC Scopus 主題領域

触媒
化学一般
生化学
コロイド化学および表面化学

文献へのアクセス

10.1021/ja00032a036

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引用スタイル

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abstract = "Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the para position in 2,2,2-trifluoroethanol gave azacarbocyclic spiro dienones in good yields. Using this method, the first total synthesis of discorhabdin C, which was isolated from the sponge of Latrunculia du Bocage in New Zealand, was achieved.",

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AU - Hatanaka, Kenji

AU - Yakura, Takayuki

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N2 - Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the para position in 2,2,2-trifluoroethanol gave azacarbocyclic spiro dienones in good yields. Using this method, the first total synthesis of discorhabdin C, which was isolated from the sponge of Latrunculia du Bocage in New Zealand, was achieved.

AB - Hypervalent iodine oxidation of O-silylated phenols bearing various types of aminoquinones at the para position in 2,2,2-trifluoroethanol gave azacarbocyclic spiro dienones in good yields. Using this method, the first total synthesis of discorhabdin C, which was isolated from the sponge of Latrunculia du Bocage in New Zealand, was achieved.

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