TY - JOUR
T1 - The Role of Autophagy in the Female Reproduction System
T2 - For Beginners to Experts in This Field
AU - Nakashima, Akitoshi
AU - Furuta, Atsushi
AU - Yamada, Kiyotaka
AU - Yoshida-Kawaguchi, Mihoko
AU - Yamaki-Ushijima, Akemi
AU - Yasuda, Ippei
AU - Ito, Masami
AU - Yamashita, Satoshi
AU - Tsuda, Sayaka
AU - Yoneda, Satoshi
AU - Cheng, Shibin
AU - Sharma, Surendra
AU - Shima, Tomoko
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/3
Y1 - 2023/3
N2 - Autophagy is a fundamental process involved in regulating cellular homeostasis. Autophagy has been classically discovered as a cellular process that degrades cytoplasmic components non-selectively to produce energy. Over the past few decades, this process has been shown to work in energy production, as well as in the reduction of excessive proteins, damaged organelles, and membrane trafficking. It contributes to many human diseases, such as neurodegenerative diseases, carcinogenesis, diabetes mellitus, development, longevity, and reproduction. In this review, we provide important information for interpreting results related to autophagic experiments and present the role of autophagy in this field.
AB - Autophagy is a fundamental process involved in regulating cellular homeostasis. Autophagy has been classically discovered as a cellular process that degrades cytoplasmic components non-selectively to produce energy. Over the past few decades, this process has been shown to work in energy production, as well as in the reduction of excessive proteins, damaged organelles, and membrane trafficking. It contributes to many human diseases, such as neurodegenerative diseases, carcinogenesis, diabetes mellitus, development, longevity, and reproduction. In this review, we provide important information for interpreting results related to autophagic experiments and present the role of autophagy in this field.
KW - ER stress
KW - LC3
KW - NBR1
KW - TFEB
KW - autophagy
KW - autophagy flux
KW - decidualization
KW - oxidative stress
KW - p62
KW - syncytiotrophoblasts
UR - http://www.scopus.com/inward/record.url?scp=85152425137&partnerID=8YFLogxK
U2 - 10.3390/biology12030373
DO - 10.3390/biology12030373
M3 - 総説
C2 - 36979065
AN - SCOPUS:85152425137
SN - 2079-7737
VL - 12
JO - Biology
JF - Biology
IS - 3
M1 - 373
ER -
