The peroxisome proliferator-activated receptor α (PPARα) agonist pemafibrate protects against diet-induced obesity in mice

Biochemistry, Genetics and Molecular Biology

• Peroxisome Proliferator-Activated Receptor 100%
• PPAR Agonist 100%
• FGF21 75%
• Blood Level 50%
• Thermogenesis 50%
• Fenofibrate 50%
• Blood Plasma 50%
• Beta Oxidation 25%
• Wild Type Mouse 25%
• Glucose Level 25%
• Lipolysis 25%
• Triacylglycerol Level 25%
• Body Weight Gain 25%
• Low Drug Dose 25%
• Hyperlipidemia 25%
• Insulin Level 25%

Keyphrases

• Peroxisome Proliferator-activated Receptor Agonists 100%
• Diet-induced Obesity 100%
• Pemafibrate 100%
• Peroxisome Proliferator-activated Receptor 33%
• Fibroblast Growth Factor 21 (FGF21) 25%
• Obesity 16%
• High-fat Diet 16%
• Metabolic Abnormalities 16%
• Plasma Parameters 16%
• Transcriptional Activity 16%
• Brown Adipose Tissue 16%
• Thermogenesis 16%
• Fenofibrate 16%
• Wild Mice 8%
• Liver 8%
• Triglyceride Level 8%
• Therapeutic Target 8%
• Expression Level 8%
• Diet-induced 8%
• Fatty Acid Oxidation 8%
• Gene Expression 8%
• Plasma Insulin 8%
• Glucose-insulin System 8%
• Lipolysis 8%
• Epididymal White Adipose Tissue 8%
• Body Weight Gain 8%
• Abdominal Adipose Tissue 8%
• Plasma Triglycerides 8%
• Plasma Glucose 8%
• Hepatic Expression 8%
• K-877 8%
• Receptor Modulators 8%
• CPT1B 8%
• CIDEA 8%
• Mitochondrial Markers 8%
• Atgl 8%
• Uncoupling Protein 1 (UCP1) 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Diet Induced Obesity 100%
• Pemafibrate 100%
• PPAR Agonist 100%
• Peroxisome Proliferator Activated Receptor 33%
• Fibroblast Growth Factor 21 25%
• Fenofibrate 16%
• Wild Type Mouse 8%
• Triacylglycerol 8%
• Hyperlipidemia 8%
• Fatty Acid 8%