The PD1 inhibitory pathway and mature dendritic cells contribute to abacavir hypersensitivity in human leukocyte antigen transgenic PD1 knockout mice

Keyphrases

• Knock-in Mouse Model 100%
• Dendritic Cells 100%
• Human Leukocyte Antigen 100%
• Abacavir Hypersensitivity 100%
• Inhibitory Pathways 100%
• Transgenic 100%
• Abacavir 83%
• Skin Hypersensitivity 83%
• Human Leukocyte antigen-B 66%
• CD8+ T Cells 50%
• CD4 T Cells 50%
• Transgenic Mice 33%
• T Cell Activation 33%
• Mouse Model 16%
• Immunomodulatory Effect 16%
• Genome-wide Association Study 16%
• Dendritic Cell Maturation 16%
• Clonal Proliferation 16%
• Anti-CD4 Antibody 16%

Immunology and Microbiology

• Transgenics 100%
• Dendritic Cell 100%
• Human Leukocyte Antigen 100%
• Knockout Mouse 100%
• Hypersensitivity 100%
• Skin Allergy 83%
• Cytotoxic T-Cell 50%
• T-Helper Cell 50%
• Transgenic Mouse 33%
• T Cell Activation 33%
• Mouse Model 16%
• Cell Maturation 16%
• Genome-Wide Association Study 16%
• Immunosuppressive Drug 16%
• CD4 Antibody 16%
• Allele 16%