抄録
A novel synthesis of quinolizidines by a cationic gold-catalyzed double cyclization cascade has been developed. The reaction was initiated by the gold-catalyzed 6-exo-dig cyclization of ynamides, which was followed by a second cyclization of an enamide intermediate to provide the corresponding quinolizidine derivatives. The utility of this reaction was demonstrated by application to the synthesis of multi-substituted quinolizidines and by the total synthesis of a quinolizidine alkaloid, (±)-lupinine.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 380-385 |
| ページ数 | 6 |
| ジャーナル | Advanced Synthesis and Catalysis |
| 巻 | 358 |
| 号 | 3 |
| DOI | |
| 出版ステータス | 出版済み - 2016/02/04 |
ASJC Scopus 主題領域
- 触媒
- 有機化学