Successful treatment of acute lung injury with pitavastatin in septic mice: Potential role of glucocorticoid receptor expression in alveolar macrophages

Keyphrases

• Successful Treatment 100%
• Acute Lung Injury 100%
• Pitavastatin 100%
• Alveolar Macrophages 100%
• Glucocorticoid Receptor Expression 100%
• Cecal Puncture 80%
• Cecal Ligation 80%
• Sepsis 60%
• Statins 60%
• Lung 40%
• Nuclear factor-B 40%
• Plasma Cortisol 40%
• Sepsis-induced Acute Lung Injury 40%
• Before Surgery 20%
• Beneficial Effects 20%
• Clinical Trials 20%
• Preventive Treatment 20%
• Intraperitoneal Injection 20%
• Animal Experiment 20%
• Sepsis Treatment 20%
• Life Support 20%
• Systemic Inflammation 20%
• Lung Damage 20%
• Increased Activity 20%
• Inflammatory Cell Infiltrate 20%
• Lipid-lowering 20%
• Pulmonary Vascular Permeability 20%
• Statin Use 20%
• Injury Management 20%
• HMG-CoA Reductase Inhibitors 20%
• Severe Hypoxemia 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Glucocorticoid Receptor 100%
• Acute Lung Injury 100%
• Pitavastatin 100%
• Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 80%
• Sepsis 60%
• Alternative Complement Pathway C3 C5 Convertase 40%
• Nuclear Factor 40%
• Hydrocortisone 40%
• Inflammation 20%
• Clinical Trial 20%
• Intraperitoneal Injection 20%
• Cecal Ligation and Puncture-Induced Sepsis 20%
• Lung Injury 20%
• Statin (Protein) 20%
• Hypoxemia 20%