抄録
The alkylation of ethyl (S)- and (R)-4,5-epoxy-2-pentenoates (11) and (12), chiral terminal γ,δ-epoxy acrylates prepared from D-mannitol, by trialkylaluminum in the presence of water occurs rcgioselectively at the γ position, i.e., at the internal position, to yield a sole product respectively with net inversion of configuration. The method provides useful chiral synthons for natural product synthesis.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 3419-3422 |
| ページ数 | 4 |
| ジャーナル | Tetrahedron Letters |
| 巻 | 38 |
| 号 | 19 |
| DOI | |
| 出版ステータス | 出版済み - 1997/05/12 |
ASJC Scopus 主題領域
- 生化学
- 創薬
- 有機化学