@article{d869bd8358424bc1a43bfdb22603b850,
title = "Stereoselective approach to potential scaffold of A-nor B-aromatic OSW-1 analogues via [4+2] cycloaddition of o-quinodimethane",
abstract = "A-nor B-aromatic steroidal skeleton was efficiently constructed by means of o-quinodimethane chemistry with exclusive stereoselectivity. The benzocyclobutene substrate for generation of the o-quinodimethane intermediate and subsequent [4+2] cycloaddition could be synthesized via (E)-selective Julia-Kocienski olefination and diastereoselective Grignard addition reactions. The synthesized tricyclic steroid-like compound with a trans-diol substructure would be utilized for divergent syntheses of potentially antitumor OSW-1 analogues with the truncated steroidal aglycone.",
keywords = "Julia-Kocienski olefination, OSW-1, Steroidal skeleton, o-Quinodimethane",
author = "Bozhi Li and Seiji Masuda and Daishiro Minato and Dejun Zhou and Kenji Sugimoto and Hideo Nemoto and Yuji Matsuya",
note = "Funding Information: This work was supported in part by a Grant-in-Aid (No. 15390004) for Scientific Research by the Ministry of Education, Culture, Sports, Science, and Technology of the Japanese Government. ",
year = "2014",
month = jul,
day = "1",
doi = "10.1016/j.tet.2014.04.079",
language = "英語",
volume = "70",
pages = "3981--3987",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Ltd.",
number = "26",
}