Regulation of cell cycle progression in astrocytes

Yuji Nakatsuji*, Robert H. Miller

*この論文の責任著者

研究成果: 書籍の章/レポート/会議録査読

2 被引用数 (Scopus)

抄録

This chapter discusses that understanding of the regulation of cell-cycle progression in astrocytes is important for the interpretation of events occurring in the course of development during recovery from the central nervous system (CNS) injury in neurodegenerative diseases and in the development of tumors. It also explores cell-cycle regulation in mammalian cells, and then discusses the cell-cycle regulation in astrocytes under normal and pathological conditions. It concludes that elucidation of the mechanisms of glial cell-cycle control has profound implications for a wide range of pathological conditions, including neurodegenerative diseases, responses to CNS injury, and formation of glial tumors. Recent studies suggest that specific regions of the CNS retain the capacity for active neurogenesis and certain neuronal precursors retain the capacity to proliferate in the adult. In general, glial cells arise after the majority of neurons are born.

本文言語英語
ホスト出版物のタイトルNon-Neuronal Cells of the Nervous System
ホスト出版物のサブタイトルFunction and Dysfunction
出版社Academic Press Inc.
ページ75-95
ページ数21
ISBN(印刷版)0444514511, 9780444514516
DOI
出版ステータス出版済み - 2003

出版物シリーズ

名前Advances in Molecular and Cell Biology
31
ISSN(印刷版)1569-2558

ASJC Scopus 主題領域

  • 分子生物学
  • 細胞生物学

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