Reeling-based cell fiber (Cell-F) assembly for the rapid construction of hierarchical tissues

Shintaroh Iwanaga*, Hiroaki Onoe, Teru Okitsu, Shoji Takeuchi

*この論文の責任著者

研究成果: 書籍の章/レポート/会議録会議への寄与査読

抄録

This conference proceeding describes a rapid fabrication of hierarchical tissues with high cell density by cell fiber (Cell-F) assembling. We prepared cell-adhesive alginate fibers and cell-encapsulated fibers using with the same microfluidic device. Cells proliferated and connected within fibers, and cell fibers kept their fiber-shapes after removing alginate. Exposed cell fibers were reeled around cell-adhesive alginate (Alg-CoP) fiber with tweezers. These cell fibers easily adhered to Alg-CoP surfaces, and we succeeded in fabricating hierarchical thick tissues with 1×108 cells/cm3 within 1 day. This approach would benefit for rapid fabrication of 3D tissue constructs with similar cell density to human body.

本文言語英語
ホスト出版物のタイトル18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
出版社Chemical and Biological Microsystems Society
ページ1140-1141
ページ数2
ISBN(電子版)9780979806476
出版ステータス出版済み - 2014
イベント18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, 米国
継続期間: 2014/10/262014/10/30

出版物シリーズ

名前18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

学会

学会18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
国/地域米国
CitySan Antonio
Period2014/10/262014/10/30

ASJC Scopus 主題領域

  • 制御およびシステム工学

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