Recent advances in cannabinoid biochemistry and biotechnology

Futoshi Taura*, Ryosuke Tanaya, Supaart Sirikantaramas

*この論文の責任著者

研究成果: ジャーナルへの寄稿学術論文査読

11 被引用数 (Scopus)

抄録

Cannabinoids, produced only in Cannabis sativa, are meroterpenoid secondary metabolites composed of monoterpene and polyketide moieties. Numerous cannabinoids have been isolated, and their pharmacological studies and clinical trials have been extensively conducted. Consequently, in recent years, certain formulations containing ∆9-tetrahydrocannabinol, the psychoactive principle of marijuana, and its isomer cannabidiol have been approved as prescribed medicines for various refractory diseases in about 30 countries. In addition, recent pioneering studies using a set of biosynthetic genes have enabled synthetic biology and synthetic biochemistry approaches to access plant-derived cannabinoids and new-to-nature analogues without the need for plant breeding. This review introduces the history of cannabinoid biosynthetic studies, and focuses on the biotechnological applications of biosynthetic enzymes.

本文言語英語
ページ(範囲)399-407
ページ数9
ジャーナルScienceAsia
45
5
DOI
出版ステータス出版済み - 2019

ASJC Scopus 主題領域

  • 一般

フィンガープリント

「Recent advances in cannabinoid biochemistry and biotechnology」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル